Predictors of in-hospital mortality in 1333 patients with acute myocardial infarction complicated by cardiogenic shock treated with primary percutaneous coronary intervention (PCI): Results of the primary PCI registry of the Arbeitsgemeinschaft Leitende Kardiologische Krankenhausärzte (ALKK)

Aims Acute myocardial infarction complicated by cardiogenic shock is associated with an exceedingly high mortality, even if patients are treated with early reperfusion therapy. The aim of this study was to evaluate predictors of in-hospital mortality of a large cohort of consecutive patients with ca...

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Published in:European heart journal 2004-02, Vol.25 (4), p.322-328
Main Authors: ZEYMER, Uwe, VOGT, Albrecht, ZAHN, Ralf, WEBER, Michael A, TEBBE, Ulrich, GOTTWIK, Martin, BONZEL, Tassilo, SENGES, Jochen, NEUHAUS, Karl-Ludwig
Format: Article
Language:English
Subjects:
Angioplasty, Balloon, Coronary - methods
Biological and medical sciences
Cardiology. Vascular system
Cohort Studies
Coronary Angiography
Coronary heart disease
Female
Heart
Hospital Mortality - trends
Humans
Male
Medical sciences
Middle Aged
Multivariate Analysis
Myocardial Infarction - complications
Myocardial Infarction - mortality
Myocardial Infarction - therapy
Myocarditis. Cardiomyopathies
Prospective Studies
Shock, Cardiogenic - complications
Shock, Cardiogenic - mortality
Stents
Treatment Outcome
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Summary:Aims Acute myocardial infarction complicated by cardiogenic shock is associated with an exceedingly high mortality, even if patients are treated with early reperfusion therapy. The aim of this study was to evaluate predictors of in-hospital mortality of a large cohort of consecutive patients with cardiogenic shock treated with primary percutaneous coronary intervention (PCI). Methods and results Between July 1994 and March 2001 all interventions performed in 80 centres in Germany were prospectively entered into the primary PCI registry of the ALKK. A total of 9422 procedures were registered, of these 1333 (14.2%) were performed in patients with cardiogenic shock. Total in-hospital mortality was 46.1% and was dependent on TIMI flow grade after PCI, with mortality rates of 78.2%, 66.1% and 37.4% in patients with TIMI 0/1, TIMI 2 and TIMI 3 flow, respectively. In a multivariate analysis left main disease, TIMI
ISSN:0195-668X
1522-9645
DOI:10.1016/j.ehj.2003.12.008