Towards a new attenuating compound: A potentiometric, spectrophotometric and NMR equilibrium study on Fe(III), Al(III) and a new tetradentate mixed bisphosphonate–hydroxypyridinonate ligand

Coordination properties toward Fe(III) and Al(III) of a mixed bisphosphonate–hydroxypyridinonate ligand are presented. Potentiometric, spectrophotometric and NMR results allowed to conclude that Fe(III) and Al(III) coordination takes place on the pyridinone moiety. The high steric hindrance prevents...

Full description

Saved in:
Bibliographic Details
Published in:Journal of inorganic biochemistry 2008-07, Vol.102 (7), p.1486-1494
Main Authors: Crisponi, Guido, Nurchi, Valeria Marina, Pivetta, Tiziana, Gałęzowska, Joanna, Gumienna-Kontecka, Elżbieta, Bailly, Théodorine, Burgada, Ramon, Kozłowski, Henryk
Format: Article
Language:English
Subjects:
1-Hydroxy-2(1H)-pyridinone
Al(III) complexes
Aluminum - chemistry
Bisphosphonates
Chelating agents
Diphosphonates - chemistry
Fe(III) complexes
Ferric Compounds - chemistry
Ligands
Magnetic Resonance Spectroscopy
Molecular Conformation
Potentiometry
Pyridones - chemistry
Quantum mechanical calculations
Quantum Theory
Spectrophotometry
Spectrum Analysis
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:Coordination properties toward Fe(III) and Al(III) of a mixed bisphosphonate–hydroxypyridinonate ligand are presented. Potentiometric, spectrophotometric and NMR results allowed to conclude that Fe(III) and Al(III) coordination takes place on the pyridinone moiety. The high steric hindrance prevents the possibility of simultaneous coordination of both groups to the same metal ion. Quantum mechanical calculations confirm this finding allowing to determine the minimal length of the linker necessary for a stable conformation of complexes in which Fe(III) is coordinated both by pyridinone and bisphosphonate groups.
ISSN:0162-0134
1873-3344
DOI:10.1016/j.jinorgbio.2008.01.010