Loading…
Heart rate variability in human immunodeficiency virus-positive individuals
Background: Heart rate variability (HRV) is a marker of cardiac autonomic tone. Depressed HRV has been reported in patients with AIDS. We conducted this study to find out if HRV is depressed in human immunodeficiency virus (HIV)-positive individuals without AIDS. Methods: We studied prospectively HR...
Saved in:
| Published in: | International journal of cardiology 2004-03, Vol.94 (1), p.1-6 |
|---|---|
| Main Authors: | , , , |
| Format: | Article |
| Language: | English |
| Subjects: | |
| Citations: | Items that this one cites Items that cite this one |
| Online Access: | Get full text |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| cited_by | cdi_FETCH-LOGICAL-c413t-3d2da35f5efbcbd31cbb06efc30fdee9c37bf87b8ed3c2564aaaf40183ee83363 |
|---|---|
| cites | cdi_FETCH-LOGICAL-c413t-3d2da35f5efbcbd31cbb06efc30fdee9c37bf87b8ed3c2564aaaf40183ee83363 |
| container_end_page | 6 |
| container_issue | 1 |
| container_start_page | 1 |
| container_title | International journal of cardiology |
| container_volume | 94 |
| creator | Mittal, Chander Mohan Wig, Naveet Mishra, Sundeep Deepak, K.K. |
| description | Background: Heart rate variability (HRV) is a marker of cardiac autonomic tone. Depressed HRV has been reported in patients with AIDS. We conducted this study to find out if HRV is depressed in human immunodeficiency virus (HIV)-positive individuals without AIDS.
Methods: We studied prospectively HRV by spectral analysis of short-term electrocardiography (ECG) monitoring in 21 HIV-positives (33±11 years) and in 18 healthy volunteers (31±9 years). None of the HIV-positives had any clinical evidence of autonomic or cardiac dysfunction. Echocardiography was also performed in HIV-seropositives to rule out left ventricular (LV) systolic dysfunction. All these individuals did not have any evidence of AIDS.
Results: Mean CD4+ lymphocyte count was 426±166/mm
3. The ejection fraction (EF%) of HIV patients was 62.4±6.4.The total power of HRV was reduced significantly in HIV-positive individuals (
p |
| doi_str_mv | 10.1016/j.ijcard.2003.02.002 |
| format | article |
| fullrecord | <record><control><sourceid>proquest_cross</sourceid><recordid>TN_cdi_proquest_miscellaneous_71693001</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><els_id>S0167527303003127</els_id><sourcerecordid>71693001</sourcerecordid><originalsourceid>FETCH-LOGICAL-c413t-3d2da35f5efbcbd31cbb06efc30fdee9c37bf87b8ed3c2564aaaf40183ee83363</originalsourceid><addsrcrecordid>eNp9kE1r3DAURUVoyEzS_INSvGl2dp4syfZsCmVIm5BAN-1ayNITfYM_ppJtmH8fTWYgu6zu5tzL5TD2hUPBgVf3u4J21gRXlACigLIAKC_Ymje1zHmt5Ce2Tlidq7IWK3Yd4w4A5GbTXLEVT1nJql6z50c0YcqCmTBbTCDTUkfTIaMh-zf3Zsio7-dhdOjJEg72kC0U5pjvx0gTLZhARwu52XTxM7v0KfD2nDfs78-HP9vH_OX3r6ftj5fcSi6mXLjSGaG8Qt_a1glu2xYq9FaAd4gbK-rWN3XboBO2VJU0xngJvBGIjRCVuGF3p919GP_PGCfdU7TYdWbAcY665tVGAPAEyhNowxhjQK_3gXoTDpqDPkrUO32SqI8SNZQ6SUy1r-f9ue3RvZfO1hLw7QyYaE3ngxksxXdOKSVBHYe-nzhMNhbCoOObRHQU0E7ajfTxk1caFJQV</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>71693001</pqid></control><display><type>article</type><title>Heart rate variability in human immunodeficiency virus-positive individuals</title><source>Elsevier</source><creator>Mittal, Chander Mohan ; Wig, Naveet ; Mishra, Sundeep ; Deepak, K.K.</creator><creatorcontrib>Mittal, Chander Mohan ; Wig, Naveet ; Mishra, Sundeep ; Deepak, K.K.</creatorcontrib><description>Background: Heart rate variability (HRV) is a marker of cardiac autonomic tone. Depressed HRV has been reported in patients with AIDS. We conducted this study to find out if HRV is depressed in human immunodeficiency virus (HIV)-positive individuals without AIDS.
Methods: We studied prospectively HRV by spectral analysis of short-term electrocardiography (ECG) monitoring in 21 HIV-positives (33±11 years) and in 18 healthy volunteers (31±9 years). None of the HIV-positives had any clinical evidence of autonomic or cardiac dysfunction. Echocardiography was also performed in HIV-seropositives to rule out left ventricular (LV) systolic dysfunction. All these individuals did not have any evidence of AIDS.
Results: Mean CD4+ lymphocyte count was 426±166/mm
3. The ejection fraction (EF%) of HIV patients was 62.4±6.4.The total power of HRV was reduced significantly in HIV-positive individuals (
p<0.00001). All the components of HRV were reduced.
Conclusions: HRV is reduced in HIV-seropositive individuals in early stages of infection as well without any clinical evidence of autonomic dysfunction. This may serve as an early marker of future global sympatho-vagal imbalance.</description><identifier>ISSN: 0167-5273</identifier><identifier>EISSN: 1874-1754</identifier><identifier>DOI: 10.1016/j.ijcard.2003.02.002</identifier><identifier>PMID: 14996467</identifier><identifier>CODEN: IJCDD5</identifier><language>eng</language><publisher>Shannon: Elsevier Ireland Ltd</publisher><subject>Adult ; Arrhythmias ; Autonomic function ; Autonomic Nervous System Diseases - physiopathology ; Biological and medical sciences ; Cardiac autonomic tone ; Cardiac dysrhythmias ; Cardiac function ; Cardiology. Vascular system ; Down-Regulation ; Echocardiography ; Electrocardiography ; Female ; Heart ; Heart Rate ; HIV Seropositivity - physiopathology ; Human viral diseases ; Humans ; Infectious diseases ; Male ; Medical sciences ; RR interval ; Vagus ; Viral diseases ; Viral diseases of the lymphoid tissue and the blood. Aids</subject><ispartof>International journal of cardiology, 2004-03, Vol.94 (1), p.1-6</ispartof><rights>2003 Elsevier Ireland Ltd</rights><rights>2004 INIST-CNRS</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c413t-3d2da35f5efbcbd31cbb06efc30fdee9c37bf87b8ed3c2564aaaf40183ee83363</citedby><cites>FETCH-LOGICAL-c413t-3d2da35f5efbcbd31cbb06efc30fdee9c37bf87b8ed3c2564aaaf40183ee83363</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,780,784,27924,27925</link.rule.ids><backlink>$$Uhttp://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&idt=15554052$$DView record in Pascal Francis$$Hfree_for_read</backlink><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/14996467$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Mittal, Chander Mohan</creatorcontrib><creatorcontrib>Wig, Naveet</creatorcontrib><creatorcontrib>Mishra, Sundeep</creatorcontrib><creatorcontrib>Deepak, K.K.</creatorcontrib><title>Heart rate variability in human immunodeficiency virus-positive individuals</title><title>International journal of cardiology</title><addtitle>Int J Cardiol</addtitle><description>Background: Heart rate variability (HRV) is a marker of cardiac autonomic tone. Depressed HRV has been reported in patients with AIDS. We conducted this study to find out if HRV is depressed in human immunodeficiency virus (HIV)-positive individuals without AIDS.
Methods: We studied prospectively HRV by spectral analysis of short-term electrocardiography (ECG) monitoring in 21 HIV-positives (33±11 years) and in 18 healthy volunteers (31±9 years). None of the HIV-positives had any clinical evidence of autonomic or cardiac dysfunction. Echocardiography was also performed in HIV-seropositives to rule out left ventricular (LV) systolic dysfunction. All these individuals did not have any evidence of AIDS.
Results: Mean CD4+ lymphocyte count was 426±166/mm
3. The ejection fraction (EF%) of HIV patients was 62.4±6.4.The total power of HRV was reduced significantly in HIV-positive individuals (
p<0.00001). All the components of HRV were reduced.
Conclusions: HRV is reduced in HIV-seropositive individuals in early stages of infection as well without any clinical evidence of autonomic dysfunction. This may serve as an early marker of future global sympatho-vagal imbalance.</description><subject>Adult</subject><subject>Arrhythmias</subject><subject>Autonomic function</subject><subject>Autonomic Nervous System Diseases - physiopathology</subject><subject>Biological and medical sciences</subject><subject>Cardiac autonomic tone</subject><subject>Cardiac dysrhythmias</subject><subject>Cardiac function</subject><subject>Cardiology. Vascular system</subject><subject>Down-Regulation</subject><subject>Echocardiography</subject><subject>Electrocardiography</subject><subject>Female</subject><subject>Heart</subject><subject>Heart Rate</subject><subject>HIV Seropositivity - physiopathology</subject><subject>Human viral diseases</subject><subject>Humans</subject><subject>Infectious diseases</subject><subject>Male</subject><subject>Medical sciences</subject><subject>RR interval</subject><subject>Vagus</subject><subject>Viral diseases</subject><subject>Viral diseases of the lymphoid tissue and the blood. Aids</subject><issn>0167-5273</issn><issn>1874-1754</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2004</creationdate><recordtype>article</recordtype><recordid>eNp9kE1r3DAURUVoyEzS_INSvGl2dp4syfZsCmVIm5BAN-1ayNITfYM_ppJtmH8fTWYgu6zu5tzL5TD2hUPBgVf3u4J21gRXlACigLIAKC_Ymje1zHmt5Ce2Tlidq7IWK3Yd4w4A5GbTXLEVT1nJql6z50c0YcqCmTBbTCDTUkfTIaMh-zf3Zsio7-dhdOjJEg72kC0U5pjvx0gTLZhARwu52XTxM7v0KfD2nDfs78-HP9vH_OX3r6ftj5fcSi6mXLjSGaG8Qt_a1glu2xYq9FaAd4gbK-rWN3XboBO2VJU0xngJvBGIjRCVuGF3p919GP_PGCfdU7TYdWbAcY665tVGAPAEyhNowxhjQK_3gXoTDpqDPkrUO32SqI8SNZQ6SUy1r-f9ue3RvZfO1hLw7QyYaE3ngxksxXdOKSVBHYe-nzhMNhbCoOObRHQU0E7ajfTxk1caFJQV</recordid><startdate>20040301</startdate><enddate>20040301</enddate><creator>Mittal, Chander Mohan</creator><creator>Wig, Naveet</creator><creator>Mishra, Sundeep</creator><creator>Deepak, K.K.</creator><general>Elsevier Ireland Ltd</general><general>Elsevier Science</general><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>20040301</creationdate><title>Heart rate variability in human immunodeficiency virus-positive individuals</title><author>Mittal, Chander Mohan ; Wig, Naveet ; Mishra, Sundeep ; Deepak, K.K.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c413t-3d2da35f5efbcbd31cbb06efc30fdee9c37bf87b8ed3c2564aaaf40183ee83363</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2004</creationdate><topic>Adult</topic><topic>Arrhythmias</topic><topic>Autonomic function</topic><topic>Autonomic Nervous System Diseases - physiopathology</topic><topic>Biological and medical sciences</topic><topic>Cardiac autonomic tone</topic><topic>Cardiac dysrhythmias</topic><topic>Cardiac function</topic><topic>Cardiology. Vascular system</topic><topic>Down-Regulation</topic><topic>Echocardiography</topic><topic>Electrocardiography</topic><topic>Female</topic><topic>Heart</topic><topic>Heart Rate</topic><topic>HIV Seropositivity - physiopathology</topic><topic>Human viral diseases</topic><topic>Humans</topic><topic>Infectious diseases</topic><topic>Male</topic><topic>Medical sciences</topic><topic>RR interval</topic><topic>Vagus</topic><topic>Viral diseases</topic><topic>Viral diseases of the lymphoid tissue and the blood. Aids</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Mittal, Chander Mohan</creatorcontrib><creatorcontrib>Wig, Naveet</creatorcontrib><creatorcontrib>Mishra, Sundeep</creatorcontrib><creatorcontrib>Deepak, K.K.</creatorcontrib><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>International journal of cardiology</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Mittal, Chander Mohan</au><au>Wig, Naveet</au><au>Mishra, Sundeep</au><au>Deepak, K.K.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Heart rate variability in human immunodeficiency virus-positive individuals</atitle><jtitle>International journal of cardiology</jtitle><addtitle>Int J Cardiol</addtitle><date>2004-03-01</date><risdate>2004</risdate><volume>94</volume><issue>1</issue><spage>1</spage><epage>6</epage><pages>1-6</pages><issn>0167-5273</issn><eissn>1874-1754</eissn><coden>IJCDD5</coden><abstract>Background: Heart rate variability (HRV) is a marker of cardiac autonomic tone. Depressed HRV has been reported in patients with AIDS. We conducted this study to find out if HRV is depressed in human immunodeficiency virus (HIV)-positive individuals without AIDS.
Methods: We studied prospectively HRV by spectral analysis of short-term electrocardiography (ECG) monitoring in 21 HIV-positives (33±11 years) and in 18 healthy volunteers (31±9 years). None of the HIV-positives had any clinical evidence of autonomic or cardiac dysfunction. Echocardiography was also performed in HIV-seropositives to rule out left ventricular (LV) systolic dysfunction. All these individuals did not have any evidence of AIDS.
Results: Mean CD4+ lymphocyte count was 426±166/mm
3. The ejection fraction (EF%) of HIV patients was 62.4±6.4.The total power of HRV was reduced significantly in HIV-positive individuals (
p<0.00001). All the components of HRV were reduced.
Conclusions: HRV is reduced in HIV-seropositive individuals in early stages of infection as well without any clinical evidence of autonomic dysfunction. This may serve as an early marker of future global sympatho-vagal imbalance.</abstract><cop>Shannon</cop><pub>Elsevier Ireland Ltd</pub><pmid>14996467</pmid><doi>10.1016/j.ijcard.2003.02.002</doi><tpages>6</tpages></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 0167-5273 |
| ispartof | International journal of cardiology, 2004-03, Vol.94 (1), p.1-6 |
| issn | 0167-5273 1874-1754 |
| language | eng |
| recordid | cdi_proquest_miscellaneous_71693001 |
| source | Elsevier |
| subjects | Adult Arrhythmias Autonomic function Autonomic Nervous System Diseases - physiopathology Biological and medical sciences Cardiac autonomic tone Cardiac dysrhythmias Cardiac function Cardiology. Vascular system Down-Regulation Echocardiography Electrocardiography Female Heart Heart Rate HIV Seropositivity - physiopathology Human viral diseases Humans Infectious diseases Male Medical sciences RR interval Vagus Viral diseases Viral diseases of the lymphoid tissue and the blood. Aids |
| title | Heart rate variability in human immunodeficiency virus-positive individuals |
| url | http://sfxeu10.hosted.exlibrisgroup.com/loughborough?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-01-04T07%3A37%3A23IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_cross&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Heart%20rate%20variability%20in%20human%20immunodeficiency%20virus-positive%20individuals&rft.jtitle=International%20journal%20of%20cardiology&rft.au=Mittal,%20Chander%20Mohan&rft.date=2004-03-01&rft.volume=94&rft.issue=1&rft.spage=1&rft.epage=6&rft.pages=1-6&rft.issn=0167-5273&rft.eissn=1874-1754&rft.coden=IJCDD5&rft_id=info:doi/10.1016/j.ijcard.2003.02.002&rft_dat=%3Cproquest_cross%3E71693001%3C/proquest_cross%3E%3Cgrp_id%3Ecdi_FETCH-LOGICAL-c413t-3d2da35f5efbcbd31cbb06efc30fdee9c37bf87b8ed3c2564aaaf40183ee83363%3C/grp_id%3E%3Coa%3E%3C/oa%3E%3Curl%3E%3C/url%3E&rft_id=info:oai/&rft_pqid=71693001&rft_id=info:pmid/14996467&rfr_iscdi=true |