Caecal Carcinomas in the Elderly: Useful Signs in Minimal Preparation CT

• Published in: Clinical radiology 2002-05, Vol.57 (5), p.359-364
• Main Authors: Ng, C.S., Doyle, T.C., Pinto, E.M., Courtney, H.M., Miller, R., Bull, R.K., Freeman, A.H., Dixon, A.K.
• Format: Article
• Language: English
• Subjects: Aged; Aged, 80 and over; Biological and medical sciences; Carcinoma - diagnostic imaging; Cecal Neoplasms - diagnostic imaging; Colonography, Computed Tomographic - methods; Colorectal Neoplasms - diagnostic imaging; computed tomography, caecal carcinoma, colorectal carcinoma, elderly; Digestive system; Female; Follow-Up Studies; Frail Elderly; Gastroenterology. Liver. Pancreas. Abdomen; Humans; Investigative techniques, diagnostic techniques (general aspects); Male; Medical sciences; Predictive Value of Tests; Radiodiagnosis. Nmr imagery. Nmr spectrometry; Retrospective Studies; Sensitivity and Specificity; Stomach. Duodenum. Small intestine. Colon. Rectum. Anus; Tumors
• ISSN: 0009-9260; 1365-229X
• DOI: 10.1053/crad.2001.0841

OBJECTIVE: Frail, elderly and immobile patients frequently have difficulty in tolerating formal colonic investigations. Caecal tumours may account for up to 35% of colonic tumours. Barium enema and colonoscopy have limitations in assessing this region. The aims of this study were to evaluate the accuracy of a minimal preparation CT technique (merely with prolonged oral contrast medium) in identifying caecal carcinomas and to determine helpful radiological signs. MATERIALS AND METHODS: The CT technique involved helical acquisition following 2 days of preparation with oral contrast medium. The outcome of 4 years' experience (1995–1998) was reviewed. The gold-standards were pathological and cancer registration records, together with colonoscopy and barium enema where available, with a minimum of 15 months' follow-up. RESULTS: CT correctly identified 27 of 30 caecal carcinomas, and missed three, in a total of 1077 CT studies in 1031 patients (median age 80 years). There were also 21 false-positive cases in which CT incorrectly raised the possibility of a caecal tumour. The sensitivity, specificity, negative predictive value (NPV) and positive predictive value (PPV) were 90%, 98%, 99% and 56%, respectively. Serosal margin blurring, tumour length, presence of abnormal peri-colic fat and terminal ileal wall thickening were identified as useful radiological signs. CONCLUSIONS: Minimal preparation CT is able to identify caecal carcinomas with fair accuracy. Such evaluation may become important given the increasing population age and evidence of a ‘proximal shift’ in the site of colonic tumours in the elderly. Ng, C. S.et al. (2002). Clinical Radiology57, 359–364.