Central pontine myelinolysis in Wilson's disease: MR spectroscopy findings

Although a pontine lesion on cranial MRI is frequently associated with an extrapontine lesion, few cases report solitary pontine involvement in Wilson disease, and it is usually recognized as central pontine lesions related to hepatic dysfunction. A patient with Wilson's disease having a solita...

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Bibliographic Details
Published in:Magnetic resonance imaging 2004, Vol.22 (1), p.117-121
Main Authors: Kizkin, Sibel, Sarac, Kaya, Ozisik, Handan Isin, Ozcan, Cemal
Format: Article
Language:English
Subjects:
Central pontine myelinolysis
Diagnosis, Differential
Hepatolenticular Degeneration - diagnosis
Humans
Magnetic Resonance Imaging
Magnetic Resonance Spectroscopy
Male
Myelinolysis, Central Pontine - diagnosis
Wilson's disease
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Summary:Although a pontine lesion on cranial MRI is frequently associated with an extrapontine lesion, few cases report solitary pontine involvement in Wilson disease, and it is usually recognized as central pontine lesions related to hepatic dysfunction. A patient with Wilson's disease having a solitary pontine lesion without basal ganglia involvement in cranial MRI with cerebellar symptoms is presented. Based on MR spectroscopy findings, this solitary pontine lesion could be regarded as central pontine myelinolysis rather than the neurologic involvement in Wilson's disease.
ISSN:0730-725X
1873-5894
DOI:10.1016/j.mri.2003.08.004