Evaluation of transforaminal ligaments by magnetic resonance imaging

• Published in: Journal of manipulative and physiological therapeutics 2002-05, Vol.25 (4), p.199-208
• Main Authors: Cramer, Gregory D., Skogsbergh, Dennis R., Bakkum, Barclay W., Winterstein, James F., Yu, ShiWei, Tuck, Nathaniel R.
• Format: Article
• Language: English
• Subjects: Aged; Aged, 80 and over; Cadaver; Corporotransverse Ligaments; Evaluation Studies as Topic; Humans; Intervertebral Foramina; Ligaments, Articular - pathology; Lumbar Vertebrae - pathology; Magnetic Resonance Imaging - methods; Male; Spinal Anatomy; Transforaminal Ligaments
• ISSN: 0161-4754; 1532-6586
• DOI: 10.1067/mmt.2002.123174

Objectives: Three-part study to (1) identify and describe transforaminal ligaments (TFLs), (2) determine the best low-field-strength magnetic resonance imaging (MRI) technique for TFLs, and (3) determine the ability of low-field-strength MRI to obtain images of TFLs. Design: Part I—descriptive anatomic study; part II—descriptive MRI study; part III—blinded comparison of diagnostic test against gold standard (MRI vs anatomic dissection). Setting: Chiropractic college gross anatomy laboratory and MRI facilities. Specimens: Three anatomic specimens of male cadavers age 60 to 85 years; a fourth specimen was used for training radiologists in part III. Main Outcome Measures: Part I—number and size of TFLs; part II—subjective grading of highest quality MRI images; part III—specificity, sensitivity, positive predictive value, negative predictive value, percent agreement, and accuracy of identifying TFLs from MRI scans. Main Results: Part I—19 TFLs identified in 30 intervertebral foramina (IVFs) (60% of IVFs had TFLs), thick = 4 (21%), medium thickness = 12 (63.2%), thin = 3 (15.8%); part II—TFLs demonstrated to best advantage with pure sagittal plane, T1-weighted MRI; part III—average: specificity = 88.9%, sensitivity = 45.6%, positive predictive value = 86.7%, negative predictive value = 50.8%, percent agreement = 78%, and accuracy = 62.4%. Conclusions: The number of TFLs was in general agreement with previous research. Images of TFLs can be successfully imaged with low-field-strength MRI. If a trained radiologist identifies a TFL, there is an 87% chance that one is present, and if a trained radiologist does not identify a TFL in an intervertebral foramen, there remains a 51% chance that one is present. (J Manipulative Physiol Ther 2002;25:199-208)