Effects of static magnetic field on human leukemic cell line HL-60

A number of structures with magnetic moments exists in living organisms that may be oriented by magnetic field. While most experimental efforts belong to the area of effects induced by weak and extremely low-frequency electromagnetic fields, we attempt to give an attention to the biological effects...

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Bibliographic Details
Published in:Bioelectrochemistry (Amsterdam, Netherlands) Netherlands), 2002-05, Vol.56 (1), p.227-231
Main Authors: Sabo, J., Mirossay, L., Horovcak, L., Sarissky, M., Mirossay, A., Mojzis, J.
Format: Article
Language:English
Subjects:
Antineoplastic Agents - pharmacology
Chemotherapy
Cytotoxicity
HL-60
HL-60 Cells
Humans
Leukemia - pathology
Magnetic fields
Magnetics
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Summary:A number of structures with magnetic moments exists in living organisms that may be oriented by magnetic field. While most experimental efforts belong to the area of effects induced by weak and extremely low-frequency electromagnetic fields, we attempt to give an attention to the biological effects of strong static magnetic fields. The influence of static magnetic field (SMF) on metabolic activity of cells was examined. The metabolic activity retardation is observed in human leukemic cell line HL-60 exposed to 1-T SMF for 72 h. The retardation effect was observed as well as in the presence of the mixture of the antineoplastic drugs 5 fluorouracil, cisplatin, doxorubicin and vincristine.
ISSN:1567-5394
DOI:10.1016/S1567-5394(02)00027-0