Hypothesis: The Protein Body Effect and Other Aspects of Food Matrix Effects

: With regard to the allergenicity of edible seeds and nuts, certain proteins may not be immediately accessible to digestion in the stomach and the upper small intestine because of the nature of the organization of such proteins into protein body organelles. Protein body hydration status, interactio...

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Bibliographic Details
Published in:Annals of the New York Academy of Sciences 2002-05, Vol.964 (1), p.111-116
Main Author: TEUBER, SUZANNE S.
Format: Article
Language:English
Subjects:
Allergens - chemistry
Food
food allergy
Food Hypersensitivity - diagnosis
Food Hypersensitivity - immunology
Food Hypersensitivity - pathology
food matrix effects
Humans
Immunoglobulin E - chemistry
protein body effect
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Summary:: With regard to the allergenicity of edible seeds and nuts, certain proteins may not be immediately accessible to digestion in the stomach and the upper small intestine because of the nature of the organization of such proteins into protein body organelles. Protein body hydration status, interactions between proteins, phytochemicals, protease inhibitors, and other matrix effects may contribute to the ability of a protein or package of proteins to reach the sites of active immune sampling in the gastrointestinal mucosa and thus be an influence on the potential allergenicity of a protein.
ISSN:0077-8923
1749-6632
DOI:10.1111/j.1749-6632.2002.tb04136.x