Determinants of coronary artery compliance in subjects with and without angiographic coronary artery disease

The goal of this study was to determine factors contributing to the biomechanical properties of coronary arteries in people with and without angiographic coronary artery disease (CAD). The stiffness of the aorta is known to increase with increasing age and in the presence of CAD. However, little is...

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Bibliographic Details
Published in:Journal of the American College of Cardiology 2002-05, Vol.39 (10), p.1637-1643
Main Authors: Shaw, James A, Kingwell, Bronwyn A, Walton, Anthony S, Cameron, James D, Pillay, Prakash, Gatzka, Christoph D, Dart, Anthony M
Format: Article
Language:English
Subjects:
Acute coronary syndromes
Adult
Age
Angioplasty
Angioplasty, Balloon, Coronary
Biological and medical sciences
Blood pressure
Cardiology
Cardiology. Vascular system
Cardiovascular disease
Catheters
Compliance
Coronary Angiography
Coronary Artery Disease - physiopathology
Coronary Artery Disease - therapy
Coronary heart disease
Coronary vessels
Coronary Vessels - physiology
Diabetes
Female
Heart
Heart attacks
Heart Transplantation
Humans
Male
Mechanical properties
Medical sciences
Middle Aged
Mortality
Pain
Postoperative Complications - physiopathology
Postoperative Complications - therapy
Reference Values
Studies
Systole - physiology
Ultrasonography, Interventional
Vascular Resistance - physiology
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Description
Summary:The goal of this study was to determine factors contributing to the biomechanical properties of coronary arteries in people with and without angiographic coronary artery disease (CAD). The stiffness of the aorta is known to increase with increasing age and in the presence of CAD. However, little is known about the mechanics of coronary arteries, which may have important clinical consequences. Intravascular ultrasound was used to determine the mechanical properties of coronary arteries and plaque behavior in subjects with CAD (n = 38), those with chest pain but angiographically normal coronary arteries (N) (n = 9) and those early (
ISSN:0735-1097
1558-3597
DOI:10.1016/S0735-1097(02)01842-9