Time-resolved 3D contrast-enhanced MRA of an extended FOV using continuous table motion

• Published in: Magnetic resonance in medicine 2004-03, Vol.51 (3), p.568-576
• Main Authors: Madhuranthakam, Ananth J., Kruger, David G., Riederer, Stephen J., Glockner, James F., Hu, Houchun H.
• Format: Article
• Language: English
• Subjects: Algorithms; contrast kinetics; Contrast Media - administration & dosage; extended-FOV MRI; Femoral Artery - anatomy & histology; Gadolinium DTPA - administration & dosage; Humans; Image Enhancement - methods; Image Processing, Computer-Assisted - methods; Imaging, Three-Dimensional; Injections, Intravenous; Leg - blood supply; Magnetic Resonance Angiography - methods; Movement; moving-table MRI; peripheral MRA; Popliteal Artery - anatomy & histology; Renal Artery - anatomy & histology; Subtraction Technique; Tibial Arteries - anatomy & histology; Time Factors; time-resolved 3D MRA
• ISSN: 0740-3194; 1522-2594
• DOI: 10.1002/mrm.10729

A method is presented for acquiring 3D time‐resolved MR images of an extended (>100 cm) longitudinal field of view (FOV), as used for peripheral MR angiographic runoff studies. Previous techniques for long‐FOV peripheral MRA have generally provided a single image (i.e., with no time resolution). The technique presented here generates a time series of 3D images of the FOV that lies within the homogeneous volume of the magnet. This is achieved by differential sampling of 3D k‐space during continuous motion of the patient table. Each point in the object is interrogated in five consecutive 3D image sets generated at 2.5‐s intervals. The method was tested experimentally in eight human subjects, and the leading edge of the bolus was observed in real time and maintained within the imaging FOV. The data revealed differential bolus velocities along the vasculature of the legs. Magn Reson Med 51:568–576, 2004. © 2004 Wiley‐Liss, Inc.