Off-label and non-classical prescriptions of antipsychotic agents in ordinary in-patient practice

Objective:  To estimate the proportion of off‐label prescriptions of antipsychotics (APs) in ordinary in‐patient practice. Method:  From the South‐Verona Psychiatric Case Register all admissions to the in‐patient unit during 2001–02 were extracted. Prescriptions of APs were defined off‐label when di...

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Bibliographic Details
Published in:Acta psychiatrica Scandinavica 2004-04, Vol.109 (4), p.275-278
Main Authors: Barbui, C., Ciuna, A., Nosé, M., Patten, S. B., Stegagno, M., Burti, L., Amaddeo, F., Tansella, M.
Format: Article
Language:English
Subjects:
Antipsychotic Agents - therapeutic use
antipsychotic drugs
Biological and medical sciences
clinical practice
Diagnosis, Differential
Drug Labeling
Drug Prescriptions - statistics & numerical data
Female
Hospitalization
Hospitals, Psychiatric
Humans
Institution therapy. Inpatient treatment
International Classification of Diseases
Length of Stay - statistics & numerical data
Male
Medical sciences
Middle Aged
Neuropharmacology
Pharmacology. Drug treatments
Practice Patterns, Physicians' - statistics & numerical data
Psycholeptics: tranquillizer, neuroleptic
Psychology. Psychoanalysis. Psychiatry
Psychopathology. Psychiatry
Psychopharmacology
psychosis
Psychotic Disorders - diagnosis
Psychotic Disorders - drug therapy
Psychotic Disorders - rehabilitation
Registries
Surveys and Questionnaires
Treatments
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Summary:Objective:  To estimate the proportion of off‐label prescriptions of antipsychotics (APs) in ordinary in‐patient practice. Method:  From the South‐Verona Psychiatric Case Register all admissions to the in‐patient unit during 2001–02 were extracted. Prescriptions of APs were defined off‐label when dispensed outside the licensed indications. In addition, the proportion of ‘non‐classical prescriptions’ was calculated. Results:  During the 2 years surveyed AP agents were prescribed in 311 cases. Nearly 50% of second‐generation AP prescriptions were for an off‐label indication. In contrast,
ISSN:0001-690X
1600-0447
DOI:10.1111/j.1600-0447.2003.00283.x