Horiolide, a Novel Norditerpenoid from Indian Ocean Soft Coral of the Genus Sinularia

A novel norditerpenoid, horiolide (1), has been isolated from an Indian Ocean soft coral of the genus Sinularia. The structural elucidation was achieved by a study of its spectral characteristics. This compound is structurally characterized by a new carbon skeleton having one six-membered cyclohexan...

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Bibliographic Details
Published in:Journal of natural products (Washington, D.C.) D.C.), 2002-05, Vol.65 (5), p.737-739
Main Authors: Radhika, Parvataneni, Subba Rao, Potluri V, Anjaneyulu, Vallurupalli, Asolkar, Ratnakar N, Laatsch, Hartmut
Format: Article
Language:English
Subjects:
Analytical, structural and metabolic biochemistry
Animals
Bacillus subtilis - drug effects
Biological and medical sciences
Chlorella - drug effects
Chromatography, Thin Layer
Circular Dichroism
Cnidaria - chemistry
Diterpenes - chemistry
Diterpenes - isolation & purification
Diterpenes - pharmacology
Escherichia coli - drug effects
Fundamental and applied biological sciences. Psychology
horiolide
Indian Ocean
Lactones - chemistry
Marine
Molecular Conformation
Molecular Structure
Mucor - drug effects
natural products
Norditerpenoids
Nuclear Magnetic Resonance, Biomolecular
Other biological molecules
Sinularia
Spectroscopy, Fourier Transform Infrared
Staphylococcus aureus - drug effects
Terpenes, steroids. Hormones
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Summary:A novel norditerpenoid, horiolide (1), has been isolated from an Indian Ocean soft coral of the genus Sinularia. The structural elucidation was achieved by a study of its spectral characteristics. This compound is structurally characterized by a new carbon skeleton having one six-membered cyclohexane ring bearing an isopropylene moiety, a carbonyl group, and one seven-membered ring attached to a five-membered lactone moiety.
ISSN:0163-3864
1520-6025
DOI:10.1021/np010528x