A case of Rosai-Dorfman disease involving the lacrimal gland in an elderly patient

Rosai-Dorfman disease (sinus histiocytosis with massive lymphadenopathy) is a rare disease characterised by benign proliferation of histiocytes, with painless lymph node enlargement and frequent extranodal involvement. Orbital involvement occurs in 11% of cases and onset of the disease is typically...

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Bibliographic Details
Published in:Orbit (Amsterdam) 2002, Vol.21 (2), p.169-175
Main Authors: Beckingsale, Peter, Sullivan, Timothy, Whitehead, Kevin
Format: Article
Language:English
Subjects:
Aged
Female
Histiocytosis, Sinus - complications
Histiocytosis, Sinus - diagnostic imaging
Histiocytosis, Sinus - pathology
Humans
Lacrimal Apparatus Diseases - complications
Lacrimal Apparatus Diseases - diagnostic imaging
Lacrimal Apparatus Diseases - pathology
Tomography, X-Ray Computed
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Summary:Rosai-Dorfman disease (sinus histiocytosis with massive lymphadenopathy) is a rare disease characterised by benign proliferation of histiocytes, with painless lymph node enlargement and frequent extranodal involvement. Orbital involvement occurs in 11% of cases and onset of the disease is typically in the first two decades of life. A benign course is usual, but in some cases blindness or fatality may result. We present a case with late onset at age 78 years and lacrimal gland involvement, and review the literature on this disease.
ISSN:0167-6830
1744-5108
DOI:10.1076/orbi.21.2.169.7182