Novel techniques in sentinel lymph node mapping and localization of nonpalpable breast lesions: the Moffitt experience

The concept of lymphatic mapping has helped to redefine the clinical significance of lymph nodes with respect to breast cancer. The combination technique using both blue dye and radiocolloid is the most effective method of lymphatic mapping. The data in the literature support the concept that all pa...

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Bibliographic Details
Published in:Annals of surgical oncology 2004-03, Vol.11 (3 Suppl), p.222S-226S
Main Authors: Cox, Charles E, Furman, Ben, Dupont, Elisabeth L, Jakub, James W, Stowell, Nicholas, Clark, John, Ebert, Mark
Format: Article
Language:English
Subjects:
Breast Neoplasms - diagnostic imaging
Breast Neoplasms - pathology
Carcinoma, Intraductal, Noninfiltrating - diagnostic imaging
Carcinoma, Intraductal, Noninfiltrating - secondary
Clinical Competence
Female
Humans
Iodine Radioisotopes
Lymph Nodes - pathology
Lymphatic Metastasis
Radionuclide Imaging
Sentinel Lymph Node Biopsy
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Summary:The concept of lymphatic mapping has helped to redefine the clinical significance of lymph nodes with respect to breast cancer. The combination technique using both blue dye and radiocolloid is the most effective method of lymphatic mapping. The data in the literature support the concept that all patients undergoing lumpectomy or especially mastectomy should undergo lymphatic mapping if a diagnosis of invasive cancer is remotely possible. The low morbidity, high sensitivity, and specificity of mapping indicate its use for increasing numbers of patients thought initially not to be candidates for the procedure.
ISSN:1068-9265
1534-4681
DOI:10.1245/aso.2004.12.913