Unusual metastatic features in a patient with concomitant malignant orbital melanoma and prostate carcinoma

A 73-year-old man with a history of malignant orbital melanoma and prostate carcinoma was admitted for progressive visual disturbance. Brain magnetic resonance imaging showed a suprasellar enhancing nodular lesion with major impingement on the anterior optical ways and sellar invasion. The extensive...

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Bibliographic Details
Published in:Journal of neuro-oncology 2004-02, Vol.66 (3), p.361-363
Main Authors: ARS, Catherine, DUCK, Lionel, BAURAIN, Jean-Francois, MOULIN, Pierre, DUPREZ, Thierry, MACHIELS, Jean-Pascal
Format: Article
Language:English
Subjects:
Adenocarcinoma - chemistry
Adenocarcinoma - secondary
Aged
Biological and medical sciences
Biomarkers, Tumor - analysis
Brain Neoplasms - chemistry
Brain Neoplasms - secondary
Humans
Lymphatic Metastasis
Magnetic Resonance Imaging
Male
Medical sciences
Melanoma - chemistry
Melanoma - secondary
Neoplasms, Multiple Primary - pathology
Neurology
Orbital Neoplasms - chemistry
Orbital Neoplasms - pathology
Pituitary Neoplasms - chemistry
Pituitary Neoplasms - secondary
Prostatic Neoplasms - chemistry
Prostatic Neoplasms - pathology
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Summary:A 73-year-old man with a history of malignant orbital melanoma and prostate carcinoma was admitted for progressive visual disturbance. Brain magnetic resonance imaging showed a suprasellar enhancing nodular lesion with major impingement on the anterior optical ways and sellar invasion. The extensive imaging work-up could not demonstrate with certainty its origin. Surprisingly, the transphenoidal biopsy of this patient revealed a prostate cancer metastasis outlining the importance of a histopathological diagnosis of cerebral metastases in patients with multiple malignancies when there is a doubt about the nature of the lesion.
ISSN:0167-594X
1573-7373
DOI:10.1023/B:NEON.0000014540.05737.1a