Reassortment and Interspecies Transmission of North American H6N2 Influenza Viruses

H6N2 influenza viruses were isolated from California chickens in 2000 and 2001. Here we report the characterization of these H6N2 viruses, one of the few descriptions of non-H5, non-H7 subtype influenza viruses in this host. The H6N2 viruses were nonpathogenic in experimentally infected chickens and...

Full description

Saved in:
Bibliographic Details
Published in:Virology (New York, N.Y.) N.Y.), 2002-03, Vol.295 (1), p.44-53
Main Authors: Webby, Richard J., Woolcock, Peter R., Krauss, Scott L., Webster, Robert G.
Format: Article
Language:English
Subjects:
Animals
avian influenza
California
Chickens - virology
Genotype
H6N2
Hemagglutinin Glycoproteins, Influenza Virus - genetics
influenza
interspecies transmission
Molecular Sequence Data
Neuraminidase - genetics
North America
Orthomyxoviridae - classification
Orthomyxoviridae - genetics
Orthomyxoviridae - pathogenicity
Orthomyxoviridae Infections - veterinary
Orthomyxoviridae Infections - virology
Phylogeny
Poultry Diseases - virology
Species Specificity
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:H6N2 influenza viruses were isolated from California chickens in 2000 and 2001. Here we report the characterization of these H6N2 viruses, one of the few descriptions of non-H5, non-H7 subtype influenza viruses in this host. The H6N2 viruses were nonpathogenic in experimentally infected chickens and could be divided into three genotypes. All three genotypes of virus had similar surface glycoproteins and all contained an 18 amino acid deletion in the neuraminidase, a characteristic of other chicken influenza viruses. Differences were apparent, however, in the complement of replicative protein genes between the genotypes. The presence of multiple H6N2 genotypes suggests that independent transmission and/or reassortment events may have taken place between aquatic bird and chicken influenza viruses.
ISSN:0042-6822
1096-0341
DOI:10.1006/viro.2001.1341