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Suppression of Immunoglobulin E-Mediated Anaphylactic Reaction by Alpinia Oxyphylla in Rats
Abstract We investigated the effect of Alpinia oxyphylla water extract (AOWE) on immunoglobulin E (IgE)-mediated anaphylaxis activated by anti-dinitrophenyl (DNP) IgE antibody. AOWE dose-dependently suppressed passive cutaneous anaphylaxis (PCA) when intraperitoneally or orally administered. On the...
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| Published in: | Immunopharmacology and immunotoxicology 2000-01, Vol.22 (2), p.267-277 |
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| Main Authors: | , , , , , , |
| Format: | Article |
| Language: | English |
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| cited_by | cdi_FETCH-LOGICAL-c433t-9b4bb133ea5befbd832db4372b04baa4cc711900e52ef358fc1d804c07ec355c3 |
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| cites | cdi_FETCH-LOGICAL-c433t-9b4bb133ea5befbd832db4372b04baa4cc711900e52ef358fc1d804c07ec355c3 |
| container_end_page | 277 |
| container_issue | 2 |
| container_start_page | 267 |
| container_title | Immunopharmacology and immunotoxicology |
| container_volume | 22 |
| creator | Kim, Sang-Hyun Choi, Yong-Kil Jeong, Hyun-Ja Kang, Hyong-Uk Moon, Goo Shin, Tae-Yong Kim, Hyung-Min |
| description | Abstract
We investigated the effect of Alpinia oxyphylla water extract (AOWE) on immunoglobulin E (IgE)-mediated anaphylaxis activated by anti-dinitrophenyl (DNP) IgE antibody. AOWE dose-dependently suppressed passive cutaneous anaphylaxis (PCA) when intraperitoneally or orally administered. On the other hand, it showed weak suppressive activity when administred intravenously. AOWE dose-dependently suppressed anaphylactic histamine release from rat peritoneal mast cells (RPMC) activated by anti-DNP IgE antibody. However, AOWE had a significant augmenting effect on anti-DNP IgE antibody-induced tumor necrosis factor-α secretion from RPMC. These results indicated that AOWE may possess strong antianaphylactic action and also suggest that differential activity following administration routes may be caused by difference of bioavailability. |
| doi_str_mv | 10.3109/08923970009016420 |
| format | article |
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We investigated the effect of Alpinia oxyphylla water extract (AOWE) on immunoglobulin E (IgE)-mediated anaphylaxis activated by anti-dinitrophenyl (DNP) IgE antibody. AOWE dose-dependently suppressed passive cutaneous anaphylaxis (PCA) when intraperitoneally or orally administered. On the other hand, it showed weak suppressive activity when administred intravenously. AOWE dose-dependently suppressed anaphylactic histamine release from rat peritoneal mast cells (RPMC) activated by anti-DNP IgE antibody. However, AOWE had a significant augmenting effect on anti-DNP IgE antibody-induced tumor necrosis factor-α secretion from RPMC. These results indicated that AOWE may possess strong antianaphylactic action and also suggest that differential activity following administration routes may be caused by difference of bioavailability.</description><identifier>ISSN: 0892-3973</identifier><identifier>EISSN: 1532-2513</identifier><identifier>DOI: 10.3109/08923970009016420</identifier><identifier>PMID: 10952031</identifier><language>eng</language><publisher>England: Informa UK Ltd</publisher><subject>Alpinia oxyphylla ; Alpinia oxyphylla water extract ; Anaphylactic reaction ; Animals ; Anti-dnitrophenyl IgE antibody ; Histamine ; Histamine Release - drug effects ; Immunoglobulin E - metabolism ; In Vitro Techniques ; Male ; Mast Cells - drug effects ; Mast Cells - immunology ; Passive Cutaneous Anaphylaxis - drug effects ; Passive Cutaneous Anaphylaxis - immunology ; Plant Extracts - administration & dosage ; Plant Extracts - pharmacology ; Plants, Medicinal ; Rats ; Rats, Sprague-Dawley ; Tumor Necrosis Factor-alpha - secretion ; Tumor necrosis factor-α ; Zingiberales</subject><ispartof>Immunopharmacology and immunotoxicology, 2000-01, Vol.22 (2), p.267-277</ispartof><rights>2000 Informa UK Ltd All rights reserved: reproduction in whole or part not permitted 2000</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c433t-9b4bb133ea5befbd832db4372b04baa4cc711900e52ef358fc1d804c07ec355c3</citedby><cites>FETCH-LOGICAL-c433t-9b4bb133ea5befbd832db4372b04baa4cc711900e52ef358fc1d804c07ec355c3</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,780,784,27923,27924</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/10952031$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Kim, Sang-Hyun</creatorcontrib><creatorcontrib>Choi, Yong-Kil</creatorcontrib><creatorcontrib>Jeong, Hyun-Ja</creatorcontrib><creatorcontrib>Kang, Hyong-Uk</creatorcontrib><creatorcontrib>Moon, Goo</creatorcontrib><creatorcontrib>Shin, Tae-Yong</creatorcontrib><creatorcontrib>Kim, Hyung-Min</creatorcontrib><title>Suppression of Immunoglobulin E-Mediated Anaphylactic Reaction by Alpinia Oxyphylla in Rats</title><title>Immunopharmacology and immunotoxicology</title><addtitle>Immunopharmacol Immunotoxicol</addtitle><description>Abstract
We investigated the effect of Alpinia oxyphylla water extract (AOWE) on immunoglobulin E (IgE)-mediated anaphylaxis activated by anti-dinitrophenyl (DNP) IgE antibody. AOWE dose-dependently suppressed passive cutaneous anaphylaxis (PCA) when intraperitoneally or orally administered. On the other hand, it showed weak suppressive activity when administred intravenously. AOWE dose-dependently suppressed anaphylactic histamine release from rat peritoneal mast cells (RPMC) activated by anti-DNP IgE antibody. However, AOWE had a significant augmenting effect on anti-DNP IgE antibody-induced tumor necrosis factor-α secretion from RPMC. These results indicated that AOWE may possess strong antianaphylactic action and also suggest that differential activity following administration routes may be caused by difference of bioavailability.</description><subject>Alpinia oxyphylla</subject><subject>Alpinia oxyphylla water extract</subject><subject>Anaphylactic reaction</subject><subject>Animals</subject><subject>Anti-dnitrophenyl IgE antibody</subject><subject>Histamine</subject><subject>Histamine Release - drug effects</subject><subject>Immunoglobulin E - metabolism</subject><subject>In Vitro Techniques</subject><subject>Male</subject><subject>Mast Cells - drug effects</subject><subject>Mast Cells - immunology</subject><subject>Passive Cutaneous Anaphylaxis - drug effects</subject><subject>Passive Cutaneous Anaphylaxis - immunology</subject><subject>Plant Extracts - administration & dosage</subject><subject>Plant Extracts - pharmacology</subject><subject>Plants, Medicinal</subject><subject>Rats</subject><subject>Rats, Sprague-Dawley</subject><subject>Tumor Necrosis Factor-alpha - secretion</subject><subject>Tumor necrosis factor-α</subject><subject>Zingiberales</subject><issn>0892-3973</issn><issn>1532-2513</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2000</creationdate><recordtype>article</recordtype><recordid>eNqFkMFO3DAURS1EBQPlA7pBWbFL-2zHk4lgM0JQkKiQoKxYRLbz0jFy7GAnovn7OgwLqqrt6i7eOVdPl5BPFD5zCtUXWFWMVyUAVECXBYMdsqCCs5wJynfJYr7nCeD75CDGJwCaYLFH9pMsGHC6II_3Y98HjNF4l_k2u-660fkf1qvRGpdd5N-wMXLAJls72W8mK_VgdHaHcyZFTdna9sYZmd3-nGbAyiyJd3KIH8mHVtqIR295SB4uL76fX-U3t1-vz9c3uS44H_JKFUpRzlEKha1qVpw1quAlU1AoKQutS0orABQMWy5WrabNCgoNJWouhOaH5GTb2wf_PGIc6s5EjekTh36MdUlLsSzSMP8DablcMngF6RbUwccYsK37YDoZpppCPU9f_zF9co7fykfVYfPO2G6dgLMtYFzrQydffLBNPcjJ-tAG6bSJc_ff-09_0zco7bDRMmD95Mfg0sL_-O4XbSykRw</recordid><startdate>20000101</startdate><enddate>20000101</enddate><creator>Kim, Sang-Hyun</creator><creator>Choi, Yong-Kil</creator><creator>Jeong, Hyun-Ja</creator><creator>Kang, Hyong-Uk</creator><creator>Moon, Goo</creator><creator>Shin, Tae-Yong</creator><creator>Kim, Hyung-Min</creator><general>Informa UK Ltd</general><general>Taylor & Francis</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7T5</scope><scope>H94</scope><scope>7X8</scope></search><sort><creationdate>20000101</creationdate><title>Suppression of Immunoglobulin E-Mediated Anaphylactic Reaction by Alpinia Oxyphylla in Rats</title><author>Kim, Sang-Hyun ; Choi, Yong-Kil ; Jeong, Hyun-Ja ; Kang, Hyong-Uk ; Moon, Goo ; Shin, Tae-Yong ; Kim, Hyung-Min</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c433t-9b4bb133ea5befbd832db4372b04baa4cc711900e52ef358fc1d804c07ec355c3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2000</creationdate><topic>Alpinia oxyphylla</topic><topic>Alpinia oxyphylla water extract</topic><topic>Anaphylactic reaction</topic><topic>Animals</topic><topic>Anti-dnitrophenyl IgE antibody</topic><topic>Histamine</topic><topic>Histamine Release - drug effects</topic><topic>Immunoglobulin E - metabolism</topic><topic>In Vitro Techniques</topic><topic>Male</topic><topic>Mast Cells - drug effects</topic><topic>Mast Cells - immunology</topic><topic>Passive Cutaneous Anaphylaxis - drug effects</topic><topic>Passive Cutaneous Anaphylaxis - immunology</topic><topic>Plant Extracts - administration & dosage</topic><topic>Plant Extracts - pharmacology</topic><topic>Plants, Medicinal</topic><topic>Rats</topic><topic>Rats, Sprague-Dawley</topic><topic>Tumor Necrosis Factor-alpha - secretion</topic><topic>Tumor necrosis factor-α</topic><topic>Zingiberales</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Kim, Sang-Hyun</creatorcontrib><creatorcontrib>Choi, Yong-Kil</creatorcontrib><creatorcontrib>Jeong, Hyun-Ja</creatorcontrib><creatorcontrib>Kang, Hyong-Uk</creatorcontrib><creatorcontrib>Moon, Goo</creatorcontrib><creatorcontrib>Shin, Tae-Yong</creatorcontrib><creatorcontrib>Kim, Hyung-Min</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>Immunology Abstracts</collection><collection>AIDS and Cancer Research Abstracts</collection><collection>MEDLINE - Academic</collection><jtitle>Immunopharmacology and immunotoxicology</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Kim, Sang-Hyun</au><au>Choi, Yong-Kil</au><au>Jeong, Hyun-Ja</au><au>Kang, Hyong-Uk</au><au>Moon, Goo</au><au>Shin, Tae-Yong</au><au>Kim, Hyung-Min</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Suppression of Immunoglobulin E-Mediated Anaphylactic Reaction by Alpinia Oxyphylla in Rats</atitle><jtitle>Immunopharmacology and immunotoxicology</jtitle><addtitle>Immunopharmacol Immunotoxicol</addtitle><date>2000-01-01</date><risdate>2000</risdate><volume>22</volume><issue>2</issue><spage>267</spage><epage>277</epage><pages>267-277</pages><issn>0892-3973</issn><eissn>1532-2513</eissn><abstract>Abstract
We investigated the effect of Alpinia oxyphylla water extract (AOWE) on immunoglobulin E (IgE)-mediated anaphylaxis activated by anti-dinitrophenyl (DNP) IgE antibody. AOWE dose-dependently suppressed passive cutaneous anaphylaxis (PCA) when intraperitoneally or orally administered. On the other hand, it showed weak suppressive activity when administred intravenously. AOWE dose-dependently suppressed anaphylactic histamine release from rat peritoneal mast cells (RPMC) activated by anti-DNP IgE antibody. However, AOWE had a significant augmenting effect on anti-DNP IgE antibody-induced tumor necrosis factor-α secretion from RPMC. These results indicated that AOWE may possess strong antianaphylactic action and also suggest that differential activity following administration routes may be caused by difference of bioavailability.</abstract><cop>England</cop><pub>Informa UK Ltd</pub><pmid>10952031</pmid><doi>10.3109/08923970009016420</doi><tpages>11</tpages></addata></record> |
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| issn | 0892-3973 1532-2513 |
| language | eng |
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| source | Taylor and Francis:Jisc Collections:Taylor and Francis Read and Publish Agreement 2024-2025:Medical Collection (Reading list) |
| subjects | Alpinia oxyphylla Alpinia oxyphylla water extract Anaphylactic reaction Animals Anti-dnitrophenyl IgE antibody Histamine Histamine Release - drug effects Immunoglobulin E - metabolism In Vitro Techniques Male Mast Cells - drug effects Mast Cells - immunology Passive Cutaneous Anaphylaxis - drug effects Passive Cutaneous Anaphylaxis - immunology Plant Extracts - administration & dosage Plant Extracts - pharmacology Plants, Medicinal Rats Rats, Sprague-Dawley Tumor Necrosis Factor-alpha - secretion Tumor necrosis factor-α Zingiberales |
| title | Suppression of Immunoglobulin E-Mediated Anaphylactic Reaction by Alpinia Oxyphylla in Rats |
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