Longstanding presence of HIV-2 infection in Guinea-Bissau (West Africa)

We have retrospectively studied the seroprevalence of the human immunodeficiency virus (HIV) in Guinea-Bissau in a sample of sera collected from the whole country in 1980. We tested a total of 1248 individuals and found 11 individuals who were seropositive for HIV-2 but there were no HIV-1 seroposit...

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Bibliographic Details
Published in:Acta tropica 2000-09, Vol.76 (2), p.119-124
Main Authors: Piedade, João, Venenno, Teresa, Prieto, Emı́lia, Albuquerque, Rita, Esteves, Aida, Parreira, Ricardo, Canas-Ferreira, Wanda F
Format: Article
Language:English
Subjects:
Adult
Age Factors
AIDS/HIV
Biological and medical sciences
Blotting, Western
Child, Preschool
Enzyme-Linked Immunosorbent Assay
Female
Guinea-Bissau
Guinea-Bissau - epidemiology
HIV Antibodies - blood
HIV Infections - blood
HIV Infections - epidemiology
HIV-2
HIV-2 - immunology
Human viral diseases
Humans
Infectious diseases
Male
Medical sciences
Middle Aged
Retrospective Studies
Rural Population
Seroepidemiologic Studies
Tropical medicine
Urban Population
Viral diseases
Viral diseases of the lymphoid tissue and the blood. Aids
West Africa
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Summary:We have retrospectively studied the seroprevalence of the human immunodeficiency virus (HIV) in Guinea-Bissau in a sample of sera collected from the whole country in 1980. We tested a total of 1248 individuals and found 11 individuals who were seropositive for HIV-2 but there were no HIV-1 seropositive samples. The mean age of the HIV-2 seropositive people was significantly higher than the age of the seronegative individuals. In the different areas surveyed, the HIV-2 seroprevalence ranged from 0 to 2.5%. A central region of the country, grossly centred in the capital city of Bissau, presented the highest prevalence of HIV-2 seropositivity (>2%), which contrasts with its virtual absence from the more remote rural areas located near the borders with the neighbouring countries. The overall seroprevalence found for HIV-2 in this study is 0.9% (1.8%, when considering the adult seroprevalence only), which proves that the virus was definitely circulating in Guinea-Bissau at the beginning of the 1980s.
ISSN:0001-706X
1873-6254
DOI:10.1016/S0001-706X(00)00096-6