Antioxidative and EROD activities of osajin and pomiferin

The major constituents of fruits of Maclura pomifera are the prenylated isoflavones, osajin ( 1) and pomiferin ( 2). Since significant biological activities of extracts from the wood of M. pomifera were previously reported, the peroxynitrite scavenging activity, inhibition of lipid peroxidation, sca...

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Bibliographic Details
Published in:Fitoterapia 2004-03, Vol.75 (2), p.209-211
Main Authors: VESELA, Dagmar, KUBINOVA, Renata, MUSELIK, Jan, ZEMLICKA, Milan, SUCHY, Vaclav
Format: Article
Language:English
Subjects:
Benzopyrans - administration & dosage
Benzopyrans - pharmacology
Benzopyrans - therapeutic use
Biological and medical sciences
Biphenyl Compounds
Cytochrome P-450 CYP1A1 - chemistry
DPPH
Free Radical Scavengers - administration & dosage
Free Radical Scavengers - pharmacology
Free Radical Scavengers - therapeutic use
Fruit
General pharmacology
Humans
Isoflavones - administration & dosage
Isoflavones - pharmacology
Isoflavones - therapeutic use
Lipid Peroxidation - drug effects
Maclura
Maclura pomifera
Medical sciences
Osajin
Peroxynitrite
Peroxynitrous Acid - chemistry
Pharmacognosy. Homeopathy. Health food
Pharmacology. Drug treatments
Phytotherapy
Picrates - chemistry
Plant Extracts - administration & dosage
Plant Extracts - pharmacology
Plant Extracts - therapeutic use
Pomiferin
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Summary:The major constituents of fruits of Maclura pomifera are the prenylated isoflavones, osajin ( 1) and pomiferin ( 2). Since significant biological activities of extracts from the wood of M. pomifera were previously reported, the peroxynitrite scavenging activity, inhibition of lipid peroxidation, scavenging of DPPH and EROD activity of these two major substances were studied.
ISSN:0367-326X
DOI:10.1016/j.fitote.2003.12.005