Performance of Thallium 201 rest-redistribution spect to predict viability in recent myocardial infarction

The detection of viability after acute myocardial infarction is primordial to select the most appropriate therapy, to decrease cardiac events and abnormal remodeling. Thallium201 SPECT is one of the radionuclide techniques used to detect viability. To evaluate the use of Thallium201 rest-redistribut...

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Bibliographic Details
Published in:Revista medíca de Chile 2002-03, Vol.130 (3), p.243-250
Main Authors: Coll, Claudia, González, Patricio, Massardo, Teresa, Sierralta, Paulina, Humeres, Pamela, Jofré, Josefina, Yovanovich, Jorge, Aramburú, Ivonne, Brugère, Solange, Chamorro, Hernán, Ramírez, Alfredo, Kunstmann, Sonia, López, Héctor
Format: Article
Language:Spanish
Subjects:
Adult
Aged
Aged, 80 and over
Female
Humans
Male
Middle Aged
Myocardial Infarction - diagnostic imaging
Predictive Value of Tests
Prospective Studies
Sensitivity and Specificity
Thallium Radioisotopes
Time Factors
Tissue Survival
Tomography, Emission-Computed, Single-Photon - methods
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Summary:The detection of viability after acute myocardial infarction is primordial to select the most appropriate therapy, to decrease cardiac events and abnormal remodeling. Thallium201 SPECT is one of the radionuclide techniques used to detect viability. To evaluate the use of Thallium201 rest-redistribution SPECT to detect myocardial viability in reperfused patients after a recent myocardial infarction. Forty one patients with up to of 24 days of evolution of a myocardial infarction were studied. All had angiographically demonstrated coronary artery disease and were subjected to a successful thrombolysis, angioplasty or bypass grafting. SPECT Thallium201 images were acquired at rest and after 4 h of redistribution. These results were compared with variations in wall motion score, studied at baseline and after 3 or 4 months with echocardiography. The sensitivity of rest-redistribution Thallium201 SPECT, to predict recovery of wall motion was 91% when patient analysis was performed and 79% when segmental analysis was done in the culprit region. The figures for specificity were 56 and 73% respectively. Rest-distribution Thallium201 SPECT has an excellent sensitivity to predict myocardial viability in recent myocardial infarction. The data obtained in this study is similar to that reported for chronic coronary artery disease.
ISSN:0034-9887