Marie Unna Hypotrichosis in a Chinese Family

: Marie Unna hypotrichosis is a rare, autosomal dominant hypotrichosis characterized by sparse or absent hair at birth with regrowth of coarse, wiry hair from childhood, followed by progressive loss on approaching puberty. We report a Chinese mother and child seen at our skin center with features of...

Full description

Saved in:
Bibliographic Details
Published in:Pediatric dermatology 2002-05, Vol.19 (3), p.250-255
Main Authors: Wong, S. N., Giam, Y. C., Lee, Y. S.
Format: Article
Language:English
Subjects:
Adult
Biological and medical sciences
China
Dermatology
Diagnosis, Differential
Female
Hair and nails disorders
Humans
Hypotrichosis - diagnosis
Hypotrichosis - genetics
Hypotrichosis - pathology
Medical sciences
Pedigree
Tropical medicine
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:: Marie Unna hypotrichosis is a rare, autosomal dominant hypotrichosis characterized by sparse or absent hair at birth with regrowth of coarse, wiry hair from childhood, followed by progressive loss on approaching puberty. We report a Chinese mother and child seen at our skin center with features of Marie Unna hypotrichosis. The family pedigree showed two affected sisters and one affected brother, consistent with an autosomal dominant mode of inheritance. The clinical, genetic, histologic, and ultrastructural features were consistent with the diagnosis of Marie Unna hypotrichosis. This is the first Chinese family reported.
ISSN:0736-8046
1525-1470
DOI:10.1046/j.1525-1470.2002.00070.x