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Characterization of Peromyscus MHC class II beta sequences by ligation-anchored RT-PCR and denaturing gradient gel electrophoresis

Summary We characterized MHC class II beta sequences in deermice (genus Peromyscus), which are amongst the most common mammals in North America. We find evidence for two different families of class II beta loci, most closely related to either the A‐type or E‐type loci in Mus. Population studies sugg...

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Bibliographic Details
Published in:European journal of immunogenetics 2002-06, Vol.29 (3), p.213-217
Main Authors: Richman, A. D., Herrera, L. G., Nash, D.
Format: Article
Language:English
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Summary:Summary We characterized MHC class II beta sequences in deermice (genus Peromyscus), which are amongst the most common mammals in North America. We find evidence for two different families of class II beta loci, most closely related to either the A‐type or E‐type loci in Mus. Population studies suggest the presence of more than one A‐type locus but only one E‐type locus for the species investigated.
ISSN:0960-7420
1365-2370
DOI:10.1046/j.1365-2370.2002.00290.x