Vitamin C and Vitamin E Protect the Rat Testes from Cadmium-induced Reactive Oxygen Species

Cadmium is an environmental and industrial pollutant that affects the male reproductive system of humans and animals. However, the mechanism of its adverse effect on Leydig cell steroidogenesis remains unknown.

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Bibliographic Details
Published in:Molecules and cells 2004-02, Vol.17 (1), p.132-139
Main Authors: Gupta, Ronojoy Sen, Dhakal, Bijaya Kumar, Ahnn, J.H. (Kwangju Institute of Science and Technology, Gwangju, Republic of Korea), Gupta, Enakshi Sen, Thakur, Ashoke Ranjan (Jadavpur University, Calcutta, India)
Format: Article
Language:English
Subjects:
17-Hydroxysteroid Dehydrogenases - metabolism
3-Hydroxysteroid Dehydrogenases - metabolism
Animals
Ascorbic Acid - pharmacology
Blotting, Northern
CADMIUM
Cadmium - metabolism
Cadmium - pharmacology
Cadmium Chloride - pharmacology
Dietary Supplements
Glutathione Peroxidase - metabolism
Lipid Metabolism
Lipid Peroxidation
Male
Malondialdehyde - pharmacology
Rats
Rats, Sprague-Dawley
Reactive Oxygen Species
RNA - metabolism
Superoxide Dismutase - metabolism
TESTES
Testis - drug effects
Testis - enzymology
Testis - pathology
Testosterone - metabolism
Vitamin E - pharmacology
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Description
Summary:Cadmium is an environmental and industrial pollutant that affects the male reproductive system of humans and animals. However, the mechanism of its adverse effect on Leydig cell steroidogenesis remains unknown.
ISSN:1016-8478
DOI:10.1016/s1016-8478(23)13017-2