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The Pediatric Autoimmune Neuropsychiatric Disorders Associated With Streptococcal Infection (PANDAS) Subgroup: Separating Fact From Fiction

Swedo et al provide a brief literature review and clarification of the guidelines for management of a patient in the pediatric autoimmune neuropsychiatric disorders associated with streptococcal infection (PANDAS) subgroup. Systematic, longitudinal observations have demonstrated that the PANDAS subg...

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Bibliographic Details
Published in:Pediatrics (Evanston) 2004-04, Vol.113 (4), p.907-911
Main Authors: Swedo, Susan E, Leonard, Henrietta L, Rapoport, Judith L
Format: Article
Language:English
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Summary:Swedo et al provide a brief literature review and clarification of the guidelines for management of a patient in the pediatric autoimmune neuropsychiatric disorders associated with streptococcal infection (PANDAS) subgroup. Systematic, longitudinal observations have demonstrated that the PANDAS subgroup has a distinct clinical presentation and an identifiable course of symptoms and that, for these children, there is a clear relationship between streptococcal infections and neuropsychiatric symptom exacerbations. Additional research is required to determine the nature of that relationship as well as to determine the etiopathogenesis of the poststreptococcal obsessive-compulsive symptoms and tics.
ISSN:0031-4005
1098-4275
DOI:10.1542/peds.113.4.907