Prevalence of diego blood group Dia antigen in Mongolians: comparison with that in Japanese

The Diego blood group is composed of Di(a) and Di(b) antigens. Prevalence of the Di(a) antigen is known to be different among races. The Di(a) antigen is generally found in Oriental people. Thus, it is called a Mongoloid factor. In Japanese, the prevalence of this antigen is 8.78%. However, the prev...

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Bibliographic Details
Published in:Transfusion and apheresis science 2004-04, Vol.30 (2), p.119-124
Main Authors: Komatsu, Fumio, Hasegawa, Kyoko, Yanagisawa, Yoshiko, Kawabata, Terue, Kaneko, Yoshinori, Watanabe, Sanae, Miyagi, Shigeji, Sakuma, Mitsuru, Kagawa, Yasuo, Kajiwara, Michiko
Format: Article
Language:English
Subjects:
Alleles
Antibody Formation
Antigens
Asian Continental Ancestry Group
Blood Group Antigens - immunology
Continental Population Groups
Gene Frequency
Haplotypes
Health technology assessment
HLA Antigens - genetics
Humans
Japan
Mongolia
Phenotype
Prevalence
Rh-Hr Blood-Group System
Urban Population
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Summary:The Diego blood group is composed of Di(a) and Di(b) antigens. Prevalence of the Di(a) antigen is known to be different among races. The Di(a) antigen is generally found in Oriental people. Thus, it is called a Mongoloid factor. In Japanese, the prevalence of this antigen is 8.78%. However, the prevalence in Mongolians had not previously been examined. In September of 2002, we determined this antigen among inhabitants of Ulaanbaatar. It was found in 24 of 242 subjects (9.92%). This prevalence approximates that in Japanese. The Rh blood group phenotypes also showed patterns similar to those in Japanese. These results are not contrary to the presumption that Mongolians and Japanese may have a common racial background.
ISSN:1473-0502
DOI:10.1016/j.transci.2003.11.004