Coronalon: a powerful tool in plant stress physiology

Coronalon, a synthetic 6-ethyl indanoyl isoleucine conjugate, has been designed as a highly active mimic of octadecanoid phytohormones that are involved in insect and disease resistance. The spectrum of biological activities that is affected by coronalon was investigated in nine different plant syst...

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Bibliographic Details
Published in:FEBS letters 2004-04, Vol.563 (1), p.17-22
Main Authors: Schüler, Göde, Mithöfer, Axel, Baldwin, Ian T, Berger, Susanne, Ebel, Jürgen, Santos, Jonathan G, Herrmann, Gabriele, Hölscher, Dirk, Kramell, Robert, Kutchan, Toni M, Maucher, Helmut, Schneider, Bernd, Stenzel, Irene, Wasternack, Claus, Boland, Wilhelm
Format: Article
Language:English
Subjects:
Cells, Cultured
Coronalon
Cyclopentanes - classification
Cyclopentanes - pharmacology
Dose-Response Relationship, Drug
Fatty Acids, Unsaturated - pharmacology
Gene Expression - drug effects
Gene Expression Regulation, Plant - drug effects
Genes, Plant
Indanoyl isoleucine conjugate
Isoleucine - analogs & derivatives
Isoleucine - chemistry
Isoleucine - pharmacology
Kinetics
Molecular Structure
Octadecanoid
Oxylipins
Plant Development
Plant Growth Regulators - pharmacology
Plant Physiological Phenomena
Plant Roots - drug effects
Plant Roots - physiology
Plant stress response
Plants - drug effects
Structure-Activity Relationship
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Summary:Coronalon, a synthetic 6-ethyl indanoyl isoleucine conjugate, has been designed as a highly active mimic of octadecanoid phytohormones that are involved in insect and disease resistance. The spectrum of biological activities that is affected by coronalon was investigated in nine different plant systems specifically responding to jasmonates and/or 12-oxo-phytodienoic acid. In all bioassays analyzed, coronalon demonstrated a general strong activity at low micromolar concentrations. The results obtained showed the induction of (i) defense-related secondary metabolite accumulation in both cell cultures and plant tissues, (ii) specific abiotic and biotic stress-related gene expression, and (iii) root growth retardation. The general activity of coronalon in the induction of plant stress responses together with its simple and efficient synthesis suggests that this compound might serve as a valuable tool in the examination of various aspects in plant stress physiology. Moreover, coronalon might become employed in agriculture to elicit plant resistance against various aggressors.
ISSN:0014-5793
1873-3468
DOI:10.1016/S0014-5793(04)00239-X