Relation of platelet inactivation with intravenous glycoprotein IIb/IIIa antagonists to major bleeding (from the GOLD study)

Analysis of the GOLD study examining the incidence of lbeeding complications found that the level of platelet inhibition was not correlated with bleeding complications. However, the degree of anticoagulation was correlated with bleeding risk.

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Bibliographic Details
Published in:The American journal of cardiology 2002-06, Vol.89 (12), p.1429-1431
Main Authors: Tamberella, Michael R, Bhatt, Deepak L, Chew, Derek P, Kereiakes, Dean J, Topol, Eric J, Steinhubl, Steven R
Format: Article
Language:English
Subjects:
Angioplasty, Balloon, Coronary
Biological and medical sciences
Blood Platelets - drug effects
Blood Platelets - physiology
Cardiology
Drug therapy
Drug toxicity and drugs side effects treatment
Female
Heart Diseases - prevention & control
Hemorrhage
Hemorrhage - etiology
Hemorrhage - prevention & control
Humans
Male
Medical sciences
Pharmacology. Drug treatments
Platelet Aggregation - drug effects
Platelet Aggregation Inhibitors - adverse effects
Platelet Aggregation Inhibitors - therapeutic use
Platelet Glycoprotein GPIIb-IIIa Complex - antagonists & inhibitors
Prospective Studies
Toxicity: blood
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Description
Summary:Analysis of the GOLD study examining the incidence of lbeeding complications found that the level of platelet inhibition was not correlated with bleeding complications. However, the degree of anticoagulation was correlated with bleeding risk.
ISSN:0002-9149
1879-1913
DOI:10.1016/S0002-9149(02)02362-7