Neurocognitive impairment influences quality of life in HIV-infected patients receiving HAART

The objective of the study was to determine the association of neurocognitive impairment with health-related quality of life (HRQoL) in patients receiving highly active antiretroviral therapy (HAART). Seventy subjects were cross-sectionally analysed with a standardized neuropsychological test batter...

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Bibliographic Details
Published in:International journal of STD & AIDS 2004-04, Vol.15 (4), p.254-259
Main Authors: TOZZI, V, BALESTRA, P, SAMPAOLESI, A, NOTO, P, IPPOLITO, G, WU, A. W, MURRI, R, GALGANI, S, BELLAGAMBA, R, NARCISO, P, ANTINORI, A, GIULIANELLI, M, TOSI, G, FANTONI, M
Format: Article
Language:English
Subjects:
Adult
AIDS/HIV
Antiretroviral Therapy, Highly Active
Biological and medical sciences
Cognition Disorders - etiology
Cross-Sectional Studies
Educational Status
Female
General aspects
HIV Infections - complications
HIV Infections - drug therapy
HIV Infections - psychology
Human immunodeficiency virus
Human viral diseases
Humans
Infectious diseases
Male
Medical sciences
Middle Aged
Multivariate Analysis
Neuropsychological Tests
Quality of Life
Surveys and Questionnaires
Viral diseases
Viral diseases of the lymphoid tissue and the blood. Aids
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Summary:The objective of the study was to determine the association of neurocognitive impairment with health-related quality of life (HRQoL) in patients receiving highly active antiretroviral therapy (HAART). Seventy subjects were cross-sectionally analysed with a standardized neuropsychological test battery and a questionnaire including an Italian translation of the MOS-HIV Health Survey. The presence of neurocognitive impairment was significantly associated with lower HRQoL scores: pain (P = 0.03), physical functioning (P = 0.01), role functioning (P = 0.01), social functioning (P = 0.029), mental health (P = 0.001), energy (P = 0.036), health distress (P = 0.002), cognitive functioning (P = 0.05), current health perception (P
ISSN:0956-4624
1758-1052
DOI:10.1258/095646204773557794