Neuroblastoma: an unusual presentation with bilateral ptosis

Neuroblastoma, a common tumor of neural crest origin, demonstrates an extremely variable clinical presentation and behavior. Paraspinal tumors may occur anywhere along the spinal column where they may invade the intervertebral foramina and produce cord compression. Cervical involvement may produce H...

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Bibliographic Details
Published in:Pediatric neurology 2004-04, Vol.30 (4), p.284-286
Main Authors: Tatli, Burak, Saribeyoğlu, Ebru Tugrul, Aydinli, Nur, Çalişkan, Mine, Anak, Sema
Format: Article
Language:English
Subjects:
Biological and medical sciences
Biopsy
Blepharoptosis - diagnosis
Blepharoptosis - etiology
Child, Preschool
Diagnosis, Differential
Diagnostic Imaging
Female
Functional Laterality - physiology
Humans
Lumbar Vertebrae - pathology
Medical sciences
Neoplasm Staging
Neuroblastoma - diagnosis
Neuroblastoma - pathology
Neurologic Examination
Neurology
Paraneoplastic Syndromes, Nervous System - diagnosis
Paraneoplastic Syndromes, Nervous System - etiology
Spinal Cord Compression - diagnosis
Spinal Cord Compression - etiology
Spinal Cord Compression - pathology
Spinal Neoplasms - diagnosis
Spinal Neoplasms - pathology
Thoracic Vertebrae - pathology
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Summary:Neuroblastoma, a common tumor of neural crest origin, demonstrates an extremely variable clinical presentation and behavior. Paraspinal tumors may occur anywhere along the spinal column where they may invade the intervertebral foramina and produce cord compression. Cervical involvement may produce Horner's syndrome. Opsoclonus-myoclonus syndrome is also a well-known neuroimmunologic finding of neuroblastoma. We report a 28-month-old female presenting with ptosis and muscle weakness, diagnosed as having a neuroblastoma.
ISSN:0887-8994
1873-5150
DOI:10.1016/j.pediatrneurol.2003.10.004