Total Synthesis of (±)-O-Methyl PD 116740

Condensation of the phthalide sulfide with an ortho-quinone monoketal was employed as a key step in the first total synthesis of a derivative of (±)-PD 116740.

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Bibliographic Details
Published in:Organic letters 2002-06, Vol.4 (13), p.2237-2239
Main Authors: Hauser, Frank M, Dorsch, Warren A, Mal, Dipakranjan
Format: Article
Language:English
Subjects:
Benz(a)Anthracenes - chemical synthesis
Benzofurans - chemistry
Hydroxylation
Quinones - chemistry
Stereoisomerism
Sulfides - chemistry
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Description
Summary:Condensation of the phthalide sulfide with an ortho-quinone monoketal was employed as a key step in the first total synthesis of a derivative of (±)-PD 116740.
ISSN:1523-7060
1523-7052
DOI:10.1021/ol026104r