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Posterior tibial nerve stimulation in the treatment of voiding dysfunction: Urodynamic data

Objectives To determine urodynamic changes and predictive factors in patients with voiding dysfunction who underwent 12 percutaneous tibial nerve stimulations. Methods Thirty nine patients with chronic voiding dysfunction were enrolled in a prospective multicenter trial in the Netherlands (n = 19) a...

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Published in:Neurourology and urodynamics 2004, Vol.23 (3), p.246-251
Main Authors: Vandoninck, Vera, van Balken, Michael R., Finazzi Agrò, Enrico, Heesakkers, John P.F.A., Debruyne, Frans M.J., Kiemeney, Lambertus A.L.M., Bemelmans, Bart L.H.
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container_start_page 246
container_title Neurourology and urodynamics
container_volume 23
creator Vandoninck, Vera
van Balken, Michael R.
Finazzi Agrò, Enrico
Heesakkers, John P.F.A.
Debruyne, Frans M.J.
Kiemeney, Lambertus A.L.M.
Bemelmans, Bart L.H.
description Objectives To determine urodynamic changes and predictive factors in patients with voiding dysfunction who underwent 12 percutaneous tibial nerve stimulations. Methods Thirty nine patients with chronic voiding dysfunction were enrolled in a prospective multicenter trial in the Netherlands (n = 19) and in Italy (n = 20). A 50% reduction in total catheterised volume per 24 hr was taken as a primary objective outcome measure. Patients' request for continuation of treatment was regarded as subjective success. Objective urodynamic parameters and bladder indices were determined. Odds ratios and their 95% confidence interval were computed as a measure for predictive power in order to reveal predictive factors (Pdet at Qmax, Qmax, BVE, and BCI). Results Primary outcome measure was obtained in 41%, an additional 26% reduced their 24 hr residuals with more than 25%. Fifty nine percent of patients chose to continue treatment. Detrusor pressure at maximal flow, cystometric residuals, and bladder indices improved significantly for all patients (P 
doi_str_mv 10.1002/nau.10158
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Methods Thirty nine patients with chronic voiding dysfunction were enrolled in a prospective multicenter trial in the Netherlands (n = 19) and in Italy (n = 20). A 50% reduction in total catheterised volume per 24 hr was taken as a primary objective outcome measure. Patients' request for continuation of treatment was regarded as subjective success. Objective urodynamic parameters and bladder indices were determined. Odds ratios and their 95% confidence interval were computed as a measure for predictive power in order to reveal predictive factors (Pdet at Qmax, Qmax, BVE, and BCI). Results Primary outcome measure was obtained in 41%, an additional 26% reduced their 24 hr residuals with more than 25%. Fifty nine percent of patients chose to continue treatment. Detrusor pressure at maximal flow, cystometric residuals, and bladder indices improved significantly for all patients (P &lt; 0.05). Patients with minor voiding dysfunction were more prone to notice success (Odds ratio: 0.73; 95% CI: 0.51–0.94). Conclusions PTNS is a young treatment modality, minimally invasive, and easily accessible. It might be an attractive first line option for patients with (minor) voiding dysfunction. Neurourol. Urodynam. 23:246–251, 2004. © 2004 Wiley‐Liss, Inc.</description><identifier>ISSN: 0733-2467</identifier><identifier>EISSN: 1520-6777</identifier><identifier>DOI: 10.1002/nau.10158</identifier><identifier>PMID: 15098221</identifier><language>eng</language><publisher>Hoboken: Wiley Subscription Services, Inc., A Wiley Company</publisher><subject>Adult ; Aged ; Electric Stimulation Therapy - adverse effects ; Female ; Humans ; Male ; Middle Aged ; nerve stimulation ; neuromodulation ; Predictive Value of Tests ; Prospective Studies ; Quality of Life ; tibial nerve ; Tibial Nerve - physiology ; Treatment Outcome ; Urinary Bladder - physiopathology ; Urination Disorders - physiopathology ; Urination Disorders - psychology ; Urination Disorders - therapy ; urodynamics ; Urodynamics - physiology ; voiding dysfunction</subject><ispartof>Neurourology and urodynamics, 2004, Vol.23 (3), p.246-251</ispartof><rights>Copyright © 2004 Wiley‐Liss, Inc.</rights><rights>Copyright 2004 Wiley-Liss, Inc.</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c3598-c45e051c6e726f748dfd4012e13dd1d00ac69f0ea363917044f0213f052342fb3</citedby><cites>FETCH-LOGICAL-c3598-c45e051c6e726f748dfd4012e13dd1d00ac69f0ea363917044f0213f052342fb3</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,780,784,4022,27922,27923,27924</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/15098221$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Vandoninck, Vera</creatorcontrib><creatorcontrib>van Balken, Michael R.</creatorcontrib><creatorcontrib>Finazzi Agrò, Enrico</creatorcontrib><creatorcontrib>Heesakkers, John P.F.A.</creatorcontrib><creatorcontrib>Debruyne, Frans M.J.</creatorcontrib><creatorcontrib>Kiemeney, Lambertus A.L.M.</creatorcontrib><creatorcontrib>Bemelmans, Bart L.H.</creatorcontrib><title>Posterior tibial nerve stimulation in the treatment of voiding dysfunction: Urodynamic data</title><title>Neurourology and urodynamics</title><addtitle>Neurourol. Urodyn</addtitle><description>Objectives To determine urodynamic changes and predictive factors in patients with voiding dysfunction who underwent 12 percutaneous tibial nerve stimulations. Methods Thirty nine patients with chronic voiding dysfunction were enrolled in a prospective multicenter trial in the Netherlands (n = 19) and in Italy (n = 20). A 50% reduction in total catheterised volume per 24 hr was taken as a primary objective outcome measure. Patients' request for continuation of treatment was regarded as subjective success. Objective urodynamic parameters and bladder indices were determined. Odds ratios and their 95% confidence interval were computed as a measure for predictive power in order to reveal predictive factors (Pdet at Qmax, Qmax, BVE, and BCI). Results Primary outcome measure was obtained in 41%, an additional 26% reduced their 24 hr residuals with more than 25%. Fifty nine percent of patients chose to continue treatment. Detrusor pressure at maximal flow, cystometric residuals, and bladder indices improved significantly for all patients (P &lt; 0.05). Patients with minor voiding dysfunction were more prone to notice success (Odds ratio: 0.73; 95% CI: 0.51–0.94). Conclusions PTNS is a young treatment modality, minimally invasive, and easily accessible. It might be an attractive first line option for patients with (minor) voiding dysfunction. Neurourol. 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Results Primary outcome measure was obtained in 41%, an additional 26% reduced their 24 hr residuals with more than 25%. Fifty nine percent of patients chose to continue treatment. Detrusor pressure at maximal flow, cystometric residuals, and bladder indices improved significantly for all patients (P &lt; 0.05). Patients with minor voiding dysfunction were more prone to notice success (Odds ratio: 0.73; 95% CI: 0.51–0.94). Conclusions PTNS is a young treatment modality, minimally invasive, and easily accessible. It might be an attractive first line option for patients with (minor) voiding dysfunction. Neurourol. Urodynam. 23:246–251, 2004. © 2004 Wiley‐Liss, Inc.</abstract><cop>Hoboken</cop><pub>Wiley Subscription Services, Inc., A Wiley Company</pub><pmid>15098221</pmid><doi>10.1002/nau.10158</doi><tpages>6</tpages></addata></record>
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source Wiley-Blackwell Read & Publish Collection
subjects Adult
Aged
Electric Stimulation Therapy - adverse effects
Female
Humans
Male
Middle Aged
nerve stimulation
neuromodulation
Predictive Value of Tests
Prospective Studies
Quality of Life
tibial nerve
Tibial Nerve - physiology
Treatment Outcome
Urinary Bladder - physiopathology
Urination Disorders - physiopathology
Urination Disorders - psychology
Urination Disorders - therapy
urodynamics
Urodynamics - physiology
voiding dysfunction
title Posterior tibial nerve stimulation in the treatment of voiding dysfunction: Urodynamic data
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