Prospective Study of Measles in Hospitalized, Human Immunodeficiency Virus (HIV)—Infected and HIV—Uninfected Children in Zambia

Measles in persons coinfected with human immunodeficiency virus (HIV) has been reported to be unusual in its presentation and frequently fatal. To determine the effect of HIV coinfection on the clinical features and outcome of measles, a prospective study of hospitalized children with measles was co...

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Bibliographic Details
Published in:Clinical infectious diseases 2002-07, Vol.35 (2), p.189-196
Main Authors: Moss, William J., Monze, Mwaka, Ryon, Judith J., Quinn, Thomas C., Griffin, Diane E., Cutts, Felicity
Format: Article
Language:English
Subjects:
AIDS-Related Opportunistic Infections - diagnosis
AIDS-Related Opportunistic Infections - epidemiology
AIDS-Related Opportunistic Infections - immunology
AIDS-Related Opportunistic Infections - prevention & control
Biological and medical sciences
CD4-Positive T-Lymphocytes - pathology
Child, Hospitalized
Child, Preschool
Children
Diarrhea
Exanthema
Female
HIV
HIV Infections - epidemiology
HIV Infections - immunology
HIV Seronegativity - immunology
HIV Seropositivity - diagnosis
HIV Seropositivity - epidemiology
HIV Seropositivity - immunology
HIV/AIDS
Hospitalization
Human viral diseases
Humans
Immunization Programs
Infant
Infectious diseases
Lymphocyte Count
Male
Measles
Measles - diagnosis
Measles - epidemiology
Measles - immunology
Measles - prevention & control
Measles Vaccine - therapeutic use
Measles virus
Measles virus - immunology
Medical sciences
Prospective Studies
T lymphocytes
T-Lymphocyte Subsets - pathology
Teaching hospitals
Tropical medicine
Vaccination
Viral diseases
Viral diseases of the lymphoid tissue and the blood. Aids
Zambia - epidemiology
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Summary:Measles in persons coinfected with human immunodeficiency virus (HIV) has been reported to be unusual in its presentation and frequently fatal. To determine the effect of HIV coinfection on the clinical features and outcome of measles, a prospective study of hospitalized children with measles was conducted between January 1998 and October 2000 in Lusaka, Zambia. One-sixth (17%) of 546 children hospitalized with laboratory-confirmed measles were coinfected with HIV. One-third of the HIV-infected children hospitalized with confirmed measles were
ISSN:1058-4838
1537-6591
DOI:10.1086/341248