Axillary lymph node recurrence of papillary thyroid microcarcinoma: report of a case

We report a case of axillary lymph node recurrence of thyroid papillary microcarcinoma (PMC) in a 51-year-old woman who had undergone thyroidectomy with lymph node dissection 5 years earlier. We performed residual thyroid resection with cervical and bilateral axillary lymph node dissection, and path...

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Bibliographic Details
Published in:Surgery today (Tokyo, Japan) Japan), 2004-05, Vol.34 (5), p.440-443
Main Authors: Koike, Kenta, Fujii, Teruhiko, Yanaga, Hiroshi, Nakagawa, Shino, Yokoyama, Goro, Yahara, Toshiro, Hanzawa, Mai, Kato, Seiya, Shirouzu, Kazuo
Format: Article
Language:English
Subjects:
Axilla
Carcinoma, Papillary - secondary
Carcinoma, Papillary - surgery
Female
Humans
Lymph Node Excision
Lymph Nodes - pathology
Lymphatic Metastasis
Middle Aged
Neoplasm Recurrence, Local - surgery
Reoperation
Thyroid Neoplasms - pathology
Thyroid Neoplasms - surgery
Thyroidectomy
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Summary:We report a case of axillary lymph node recurrence of thyroid papillary microcarcinoma (PMC) in a 51-year-old woman who had undergone thyroidectomy with lymph node dissection 5 years earlier. We performed residual thyroid resection with cervical and bilateral axillary lymph node dissection, and pathological examination revealed well-differentiated papillary carcinoma, with partial poor differentiation. Postoperative radioiodine therapy was ineffective, and the patient died of systemic dissemination of the recurrence 8 months after her second operation. The positive cell rates of proliferating cell nuclear antigen and Ki-67 were clearly higher in the recurrent lymph nodes than in the primary thyroid tumor, suggesting increased cell proliferation in the recurrent lymph nodes. Thyroid papillary carcinoma rarely recurs in the axillary lymph nodes, but its possibility must be kept in mind, especially in patients with remarkable cervical lymph node metastasis and those who undergo extensive lymph node dissection.
ISSN:0941-1291
1436-2813
DOI:10.1007/s00595-003-2735-8