Embolization of intracranial aneurysms and sickle cell disease

• Published in: American journal of hematology 2004-05, Vol.76 (1), p.83-84
• Main Authors: Vicari, Perla, Choairy, Ana Cristina C., Siufi, Grazziella C., Arantes, Adriano M., Fonseca, José Roberto F., Figueiredo, Maria Stella
• Format: Article
• Language: English
• Subjects: Adult; Anemia, Sickle Cell - complications; Anemia, Sickle Cell - diagnostic imaging; Anemia, Sickle Cell - therapy; Anemias. Hemoglobinopathies; Biological and medical sciences; Cerebral Angiography; Diseases of red blood cells; Embolization, Therapeutic - instrumentation; Embolization, Therapeutic - methods; endovascular embolization; Hematologic and hematopoietic diseases; Humans; intracranial aneurysm; Intracranial Aneurysm - diagnostic imaging; Intracranial Aneurysm - etiology; Intracranial Aneurysm - therapy; Male; Medical sciences; Neurology; sickle cell disease; subarachnoid hemorrhage; Subarachnoid Hemorrhage - diagnostic imaging; Subarachnoid Hemorrhage - etiology; Subarachnoid Hemorrhage - therapy; Tomography, X-Ray Computed; Vascular diseases and vascular malformations of the nervous system
• ISSN: 0361-8609; 1096-8652
• DOI: 10.1002/ajh.20033

The association of intracranial aneurysms and sickle cell disease (SCD) has been described in the English‐language literature. Treatment strategies have included angiography and craniotomy. However, with advancement of non‐operative interventions, much controversy surrounds the treatment of these patients. Endovascular embolization has been used in many patients with cerebral aneurysms, but it had been reported in the literature in only two sickle cell patients. The authors present a case of endovascular embolization of multiple intracranial aneurysms in a patient with sickle cell anemia with good outcome. Am. J. Hematol. 76:83–84, 2004. © 2004 Wiley‐Liss, Inc.