Effects of sodium fluoride on total serum protein levels and transaminase activity in rats

Transaminase activity and serum total protein level were investigated in adult rats after oral treating with sodium fluoride at three doses, 10, 20 and 30 mg/kg daily for 90 days. After 90 days, the average total serum protein level of the rats in the treatment group decreased significantly compared...

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Bibliographic Details
Published in:Biomedicine & pharmacotherapy 2002-06, Vol.56 (4), p.169-172
Main Authors: Qujeq, D, Laghaie, B, Gholipour, A, Solimani, N, Hassenzadeh, S
Format: Article
Language:English
Subjects:
Animals
Biological and medical sciences
Blood Proteins - metabolism
Body Weight - drug effects
Body Weight - physiology
Dose-Response Relationship, Drug
Drug toxicity and drugs side effects treatment
Eating - drug effects
Eating - physiology
Enzyme Activation - drug effects
Enzyme Activation - physiology
Medical sciences
Pharmacology. Drug treatments
Rats
Serum total protein
Sodium fluoride
Sodium Fluoride - pharmacology
Toxicity: blood
Transaminase
Transaminases - blood
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Summary:Transaminase activity and serum total protein level were investigated in adult rats after oral treating with sodium fluoride at three doses, 10, 20 and 30 mg/kg daily for 90 days. After 90 days, the average total serum protein level of the rats in the treatment group decreased significantly compared with that in the control 〚1.9 ± 0.1 (mean ± S.D., n = 140) vs. 3.1 ± 0.2〛 mg/dl, P
ISSN:0753-3322
1950-6007
DOI:10.1016/S0753-3322(02)00172-5