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Atypical cognitive profile in patients with depression after myocardial infarction

Background: We evaluated the cognitive profile of 48 patients with major depression following their first myocardial infarction (MI). Methods: The cognitive performance of the patients was compared with the performance of 48 non-depressed MI patients and 48 healthy controls. Results: Depressed MI pa...

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Bibliographic Details
Published in:Journal of affective disorders 2002-07, Vol.70 (2), p.181-190
Main Authors: Dijkstra, Jeanette B, Strik, Jacqueline J.M.H, Lousberg, Richel, Prickaerts, Jos, Riedel, Wim J, Jolles, Jelle, van Praag, Herman M, Honig, Adriaan
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Language:English
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Summary:Background: We evaluated the cognitive profile of 48 patients with major depression following their first myocardial infarction (MI). Methods: The cognitive performance of the patients was compared with the performance of 48 non-depressed MI patients and 48 healthy controls. Results: Depressed MI patients performed slower on a simple cognitive speed related measure compared with non-depressed MI patients and healthy controls. Attention and speed-related aspects of cognitive functioning were not affected. Surprisingly, (depressed) MI patients showed even better performances with respect to memory function. Limitation: No patients with non-MI-related depression were included. Conclusions: The cognitive profile of major depression after MI differs from that of non-cardiac-related depressive disorder, as described in the literature. This may reflect a different etiology of post MI depression from non-cardiac-related depression.
ISSN:0165-0327
1573-2517
DOI:10.1016/S0165-0327(01)00348-2