Acquired pure megakaryocytic aplasia: a separate haematological disease entity or a syndrome with multiple causes?

: We report the case of a patient with acquired pure megakaryocytic aplasia. Until today, less than 20 cases of acquired pure megakaryocytic aplasia have been reported and the disease aetiology still seems to be unclear. This report summarizes the published data concerning possible aetiologies, trea...

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Bibliographic Details
Published in:European journal of haematology 2004-06, Vol.72 (6), p.451-454
Main Authors: Felderbauer, P., Ritter, P. R., Mattern, D., Schmitz, F., Bulut, K., Ansorge, N., Schmitt‐Graeff, A., Schmidt, W. E., Baier, J. E.
Format: Article
Language:English
Subjects:
acquired amegakaryocytic thrombocytopenic purpura
acquired pure amegakaryocytic aplasia
Adult
Blood Transfusion
Bone Marrow Diseases - etiology
Bone Marrow Diseases - pathology
Bone Marrow Examination
Bone Marrow Transplantation - adverse effects
Disease Progression
Fatal Outcome
Humans
Immunosuppressive Agents - therapeutic use
Male
Megakaryocytes - pathology
myelodysplasia
Purpura
Thrombocytopenia - etiology
Thrombocytopenia - therapy
Transplantation, Homologous
Treatment Outcome
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Summary:: We report the case of a patient with acquired pure megakaryocytic aplasia. Until today, less than 20 cases of acquired pure megakaryocytic aplasia have been reported and the disease aetiology still seems to be unclear. This report summarizes the published data concerning possible aetiologies, treatment options and outcome of patients with acquired pure megakaryocytic aplasia. Furthermore, this case report presents an example for a possible disease progression.
ISSN:0902-4441
1600-0609
DOI:10.1111/j.1600-0609.2004.00241.x