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The relation between latent inhibition and symptom-types in young schizophrenics

Latent inhibition (LI), retarded conditioning to a stimulus that has been previously repeatedly presented without reinforcement, was examined in young schizophrenics and normal controls using a within-subject visual search task. Healthy controls exhibited the usual LI effect. LI was potentiated in s...

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Published in:	Behavioural brain research 2004-03, Vol.149 (2), p.113-122
Main Authors:	Cohen, Efrat, Sereni, Noam, Kaplan, O, Weizman, A, Kikinzon, L, Weiner, I, Lubow, R.E
Format:	Article
Language:	English
Subjects:	Adolescent Adult Adult and adolescent clinical studies Analysis of Variance Attention Biological and medical sciences Female Hospitalization - statistics & numerical data Humans Inhibition (Psychology) Latent inhibition Male Medical sciences Negative symptoms Positive symptoms Psychiatric Status Rating Scales Psychology. Psychoanalysis. Psychiatry Psychopathology. Psychiatry Psychoses Reaction Time - physiology Schizophrenia Schizophrenia - physiopathology Schizophrenic Psychology Task Performance and Analysis Visual Perception - physiology
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container_title	Behavioural brain research
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creator	Cohen, Efrat Sereni, Noam Kaplan, O Weizman, A Kikinzon, L Weiner, I Lubow, R.E
description	Latent inhibition (LI), retarded conditioning to a stimulus that has been previously repeatedly presented without reinforcement, was examined in young schizophrenics and normal controls using a within-subject visual search task. Healthy controls exhibited the usual LI effect. LI was potentiated in schizophrenics who simultaneously exhibited high levels of negative symptoms and low levels of positive symptoms. Schizophrenic groups with other combinations of positive and negative symptoms did not differ from controls. The pattern of data suggests that past inconsistencies in the LI-schizophrenia literature may be the result of opposing processes that are associated with positive and negative symptoms.
doi_str_mv	10.1016/S0166-4328(03)00221-3
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Psychiatry</topic><topic>Psychoses</topic><topic>Reaction Time - physiology</topic><topic>Schizophrenia</topic><topic>Schizophrenia - physiopathology</topic><topic>Schizophrenic Psychology</topic><topic>Task Performance and Analysis</topic><topic>Visual Perception - physiology</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Cohen, Efrat</creatorcontrib><creatorcontrib>Sereni, Noam</creatorcontrib><creatorcontrib>Kaplan, O</creatorcontrib><creatorcontrib>Weizman, A</creatorcontrib><creatorcontrib>Kikinzon, L</creatorcontrib><creatorcontrib>Weiner, I</creatorcontrib><creatorcontrib>Lubow, R.E</creatorcontrib><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>Neurosciences Abstracts</collection><collection>MEDLINE - Academic</collection><jtitle>Behavioural brain research</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Cohen, Efrat</au><au>Sereni, Noam</au><au>Kaplan, O</au><au>Weizman, A</au><au>Kikinzon, L</au><au>Weiner, I</au><au>Lubow, R.E</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>The relation between latent inhibition and symptom-types in young schizophrenics</atitle><jtitle>Behavioural brain research</jtitle><addtitle>Behav Brain Res</addtitle><date>2004-03-02</date><risdate>2004</risdate><volume>149</volume><issue>2</issue><spage>113</spage><epage>122</epage><pages>113-122</pages><issn>0166-4328</issn><eissn>1872-7549</eissn><coden>BBREDI</coden><abstract>Latent inhibition (LI), retarded conditioning to a stimulus that has been previously repeatedly presented without reinforcement, was examined in young schizophrenics and normal controls using a within-subject visual search task. 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subjects	Adolescent Adult Adult and adolescent clinical studies Analysis of Variance Attention Biological and medical sciences Female Hospitalization - statistics & numerical data Humans Inhibition (Psychology) Latent inhibition Male Medical sciences Negative symptoms Positive symptoms Psychiatric Status Rating Scales Psychology. Psychoanalysis. Psychiatry Psychopathology. Psychiatry Psychoses Reaction Time - physiology Schizophrenia Schizophrenia - physiopathology Schizophrenic Psychology Task Performance and Analysis Visual Perception - physiology
title	The relation between latent inhibition and symptom-types in young schizophrenics
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