Mass spectrometry and DNA sequencing are complementary techniques for characterizing hemoglobin variants: the example of hemoglobin J-Oxford

Liquid chromatography-electrospray ionization-mass spectrometry (MS) allows the characterization of most hemoglobin variants and can sometimes be a useful tool to narrow down DNA sequencing analysis. As an example, we report a case of hemoglobin variant J-Oxford, characterized by MS and DNA sequenci...

Full description

Saved in:
Bibliographic Details
Published in:Haematologica (Roma) 2004-05, Vol.89 (5), p.608-609
Main Authors: Caruso, D, Crestani, M, Da Riva, L, Mitro, N, Giavarini, F, Mozzi, R, Franzini, C
Format: Article
Language:English
Subjects:
Adult
Codon - genetics
Female
Hemoglobin J - chemistry
Hemoglobin J - genetics
Humans
Mutation
Sequence Analysis, DNA
Spectrometry, Mass, Electrospray Ionization
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:Liquid chromatography-electrospray ionization-mass spectrometry (MS) allows the characterization of most hemoglobin variants and can sometimes be a useful tool to narrow down DNA sequencing analysis. As an example, we report a case of hemoglobin variant J-Oxford, characterized by MS and DNA sequencing analysis.
ISSN:0390-6078
1592-8721