Benign renal mesenchymoma in the pediatric age group: a novel pathologic and karyotype entity

Benign mesenchymal renal tumors are extremely rare in the pediatric age group. We report a case of a benign renal tumor composed of smooth muscle cells, adipose tissue, and areas of cartilaginous differentiation and expressing a 46,XX, t(8;10)(q21;q24) karyotype in a 13-year-old girl. Although some...

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Bibliographic Details
Published in:Urology (Ridgewood, N.J.) N.J.), 2004-05, Vol.63 (5), p.981-984
Main Authors: Joniau, Steven, Goeman, Lieven, Kreuzbauer, Susanne, Bogaert, Guy, Dal Cin, Paola, Oyen, Raymond, Sciot, Raf, van Poppel, Hein
Format: Article
Language:English
Subjects:
Adolescent
Appendicitis - surgery
Female
Humans
Incidental Findings
Karyotyping
Kidney Neoplasms - genetics
Kidney Neoplasms - pathology
Mesenchymoma - genetics
Mesenchymoma - pathology
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Summary:Benign mesenchymal renal tumors are extremely rare in the pediatric age group. We report a case of a benign renal tumor composed of smooth muscle cells, adipose tissue, and areas of cartilaginous differentiation and expressing a 46,XX, t(8;10)(q21;q24) karyotype in a 13-year-old girl. Although some pediatric renal tumors show a degree of heterologous differentiation, none of them exclusively consist of these three well-differentiated mesenchymal components. The unique features of the present case were further confirmed by the karyotype changes, which to our knowledge, have never been described before in a pediatric renal tumor.
ISSN:0090-4295
1527-9995
DOI:10.1016/j.urology.2004.01.006