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Treatment of small lungworm infestation in sheep by using moxidectin
The use of moxidectin (MXD) in the treatment of small lungworm infestation ( Cystocaulus ocreatus, Muellerius capillaris, Neostrongylus linearis and Protostronglylus rufescens) in sheep, was evaluated. Twenty-one sheep naturally infested with small lungworms, were divided into three groups ( n=7) an...
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| Published in: | Veterinary parasitology 2004-05, Vol.121 (3), p.329-336 |
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| cites | cdi_FETCH-LOGICAL-c382t-369370013e3381eeb15ddabf3c0c2f7d6a2563658f269c2deca466ffcc0f23af3 |
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| container_start_page | 329 |
| container_title | Veterinary parasitology |
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| creator | Papadopoulos, E Sotiraki, S Himonas, C Fthenakis, G.C |
| description | The use of moxidectin (MXD) in the treatment of small lungworm infestation (
Cystocaulus ocreatus,
Muellerius capillaris,
Neostrongylus linearis and
Protostronglylus rufescens) in sheep, was evaluated. Twenty-one sheep naturally infested with small lungworms, were divided into three groups (
n=7) and treated as follows: group A with moxidectin 1% injectable solution at a dose rate of 0.2
mg
kg
−1 bodyweight, group B with moxidectin 0.1% oral drench at a dose rate of 0.2
mg
kg
−1 bodyweight and group C being controls. Before treatment, mean faecal larval counts were 30.7, 21.1 and 26.7
lpg in group A, B and C, respectively; 14 days after treatment respective counts were 0.4, 2.3 and 63.0
lpg, (percentage reduction after moxidectin administration >96.0%); 60 days after treatment respective counts were 0.0, 0.0 and 26.4
lpg, (percentage reduction after moxidectin administration 100%). It is concluded that treatment of small lungworm infestation of sheep can be effected by using moxidectin. |
| doi_str_mv | 10.1016/j.vetpar.2004.02.026 |
| format | article |
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Cystocaulus ocreatus,
Muellerius capillaris,
Neostrongylus linearis and
Protostronglylus rufescens) in sheep, was evaluated. Twenty-one sheep naturally infested with small lungworms, were divided into three groups (
n=7) and treated as follows: group A with moxidectin 1% injectable solution at a dose rate of 0.2
mg
kg
−1 bodyweight, group B with moxidectin 0.1% oral drench at a dose rate of 0.2
mg
kg
−1 bodyweight and group C being controls. Before treatment, mean faecal larval counts were 30.7, 21.1 and 26.7
lpg in group A, B and C, respectively; 14 days after treatment respective counts were 0.4, 2.3 and 63.0
lpg, (percentage reduction after moxidectin administration >96.0%); 60 days after treatment respective counts were 0.0, 0.0 and 26.4
lpg, (percentage reduction after moxidectin administration 100%). It is concluded that treatment of small lungworm infestation of sheep can be effected by using moxidectin.</description><identifier>ISSN: 0304-4017</identifier><identifier>EISSN: 1873-2550</identifier><identifier>DOI: 10.1016/j.vetpar.2004.02.026</identifier><identifier>PMID: 15135874</identifier><language>eng</language><publisher>Netherlands: Elsevier B.V</publisher><subject>Administration, Oral ; animal parasitic nematodes ; Animals ; Antinematodal Agents - therapeutic use ; Control methods-Nematoda ; Cystocaulus ; Cystocaulus ocreatus ; drug efficacy ; drug formulations ; drug therapy ; fecal larval count ; Feces - parasitology ; Female ; Injections, Subcutaneous - veterinary ; Lung - parasitology ; Lungworms ; Macrolides - therapeutic use ; Moxidectin ; Muellerius capillaris ; nematode infections ; nematode larvae ; Neostrongylus ; Neostrongylus linearis ; oral administration ; Parasite Egg Count - veterinary ; population density ; Protostrongylus ; Protostrongylus rufescens ; Sheep ; Sheep Diseases - drug therapy ; Sheep Diseases - parasitology ; Sheep-Nematoda ; Statistics, Nonparametric ; subcutaneous injection ; Trachea - parasitology ; Trichostrongyloidea - growth & development ; Trichostrongyloidiasis - drug therapy ; Trichostrongyloidiasis - parasitology ; Trichostrongyloidiasis - veterinary</subject><ispartof>Veterinary parasitology, 2004-05, Vol.121 (3), p.329-336</ispartof><rights>2004 Elsevier B.V.</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c382t-369370013e3381eeb15ddabf3c0c2f7d6a2563658f269c2deca466ffcc0f23af3</citedby><cites>FETCH-LOGICAL-c382t-369370013e3381eeb15ddabf3c0c2f7d6a2563658f269c2deca466ffcc0f23af3</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,780,784,27924,27925</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/15135874$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Papadopoulos, E</creatorcontrib><creatorcontrib>Sotiraki, S</creatorcontrib><creatorcontrib>Himonas, C</creatorcontrib><creatorcontrib>Fthenakis, G.C</creatorcontrib><title>Treatment of small lungworm infestation in sheep by using moxidectin</title><title>Veterinary parasitology</title><addtitle>Vet Parasitol</addtitle><description>The use of moxidectin (MXD) in the treatment of small lungworm infestation (
Cystocaulus ocreatus,
Muellerius capillaris,
Neostrongylus linearis and
Protostronglylus rufescens) in sheep, was evaluated. Twenty-one sheep naturally infested with small lungworms, were divided into three groups (
n=7) and treated as follows: group A with moxidectin 1% injectable solution at a dose rate of 0.2
mg
kg
−1 bodyweight, group B with moxidectin 0.1% oral drench at a dose rate of 0.2
mg
kg
−1 bodyweight and group C being controls. Before treatment, mean faecal larval counts were 30.7, 21.1 and 26.7
lpg in group A, B and C, respectively; 14 days after treatment respective counts were 0.4, 2.3 and 63.0
lpg, (percentage reduction after moxidectin administration >96.0%); 60 days after treatment respective counts were 0.0, 0.0 and 26.4
lpg, (percentage reduction after moxidectin administration 100%). It is concluded that treatment of small lungworm infestation of sheep can be effected by using moxidectin.</description><subject>Administration, Oral</subject><subject>animal parasitic nematodes</subject><subject>Animals</subject><subject>Antinematodal Agents - therapeutic use</subject><subject>Control methods-Nematoda</subject><subject>Cystocaulus</subject><subject>Cystocaulus ocreatus</subject><subject>drug efficacy</subject><subject>drug formulations</subject><subject>drug therapy</subject><subject>fecal larval count</subject><subject>Feces - parasitology</subject><subject>Female</subject><subject>Injections, Subcutaneous - veterinary</subject><subject>Lung - parasitology</subject><subject>Lungworms</subject><subject>Macrolides - therapeutic use</subject><subject>Moxidectin</subject><subject>Muellerius capillaris</subject><subject>nematode infections</subject><subject>nematode larvae</subject><subject>Neostrongylus</subject><subject>Neostrongylus linearis</subject><subject>oral administration</subject><subject>Parasite Egg Count - veterinary</subject><subject>population density</subject><subject>Protostrongylus</subject><subject>Protostrongylus rufescens</subject><subject>Sheep</subject><subject>Sheep Diseases - drug therapy</subject><subject>Sheep Diseases - parasitology</subject><subject>Sheep-Nematoda</subject><subject>Statistics, Nonparametric</subject><subject>subcutaneous injection</subject><subject>Trachea - parasitology</subject><subject>Trichostrongyloidea - growth & development</subject><subject>Trichostrongyloidiasis - drug therapy</subject><subject>Trichostrongyloidiasis - parasitology</subject><subject>Trichostrongyloidiasis - veterinary</subject><issn>0304-4017</issn><issn>1873-2550</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2004</creationdate><recordtype>article</recordtype><recordid>eNp9kE1LxDAQhoMoun78A9GevHWdJE3avQiyfoLgQT2HbDpZs7TNmrR-_HuzdMGbMDBzeOZl5iHklMKUApWXq-kn9msdpgygmAJLJXfIhFYlz5kQsEsmwKHIC6DlATmMcQUJBFnukwMqKBdVWUzIzWtA3bfY9Zm3WWx102TN0C2_fGgz11mMve6d79KcxXfEdbb4yYboumXW-m9Xo-ldd0z2rG4inmz7EXm7u32dP-RPz_eP8-un3PCK9TmXM14CUI6cVxRxQUVd64XlBgyzZS01E5JLUVkmZ4albF1Iaa0xYBnXlh-RizF3HfzHkE5TrYsGm0Z36IeoSjqjKUAmsBhBE3yMAa1aB9fq8KMoqI09tVKjPbWxp4Cl2qydbfOHRYv139JWVwLOR8Bqr_QyuKjeXlj6CGDGJQiRiKuRwOTh02FQ0TjsDNYuJFeq9u7_G34BnkWMdw</recordid><startdate>20040526</startdate><enddate>20040526</enddate><creator>Papadopoulos, E</creator><creator>Sotiraki, S</creator><creator>Himonas, C</creator><creator>Fthenakis, G.C</creator><general>Elsevier B.V</general><scope>FBQ</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>20040526</creationdate><title>Treatment of small lungworm infestation in sheep by using moxidectin</title><author>Papadopoulos, E ; Sotiraki, S ; Himonas, C ; Fthenakis, G.C</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c382t-369370013e3381eeb15ddabf3c0c2f7d6a2563658f269c2deca466ffcc0f23af3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2004</creationdate><topic>Administration, Oral</topic><topic>animal parasitic nematodes</topic><topic>Animals</topic><topic>Antinematodal Agents - therapeutic use</topic><topic>Control methods-Nematoda</topic><topic>Cystocaulus</topic><topic>Cystocaulus ocreatus</topic><topic>drug efficacy</topic><topic>drug formulations</topic><topic>drug therapy</topic><topic>fecal larval count</topic><topic>Feces - parasitology</topic><topic>Female</topic><topic>Injections, Subcutaneous - veterinary</topic><topic>Lung - parasitology</topic><topic>Lungworms</topic><topic>Macrolides - therapeutic use</topic><topic>Moxidectin</topic><topic>Muellerius capillaris</topic><topic>nematode infections</topic><topic>nematode larvae</topic><topic>Neostrongylus</topic><topic>Neostrongylus linearis</topic><topic>oral administration</topic><topic>Parasite Egg Count - veterinary</topic><topic>population density</topic><topic>Protostrongylus</topic><topic>Protostrongylus rufescens</topic><topic>Sheep</topic><topic>Sheep Diseases - drug therapy</topic><topic>Sheep Diseases - parasitology</topic><topic>Sheep-Nematoda</topic><topic>Statistics, Nonparametric</topic><topic>subcutaneous injection</topic><topic>Trachea - parasitology</topic><topic>Trichostrongyloidea - growth & development</topic><topic>Trichostrongyloidiasis - drug therapy</topic><topic>Trichostrongyloidiasis - parasitology</topic><topic>Trichostrongyloidiasis - veterinary</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Papadopoulos, E</creatorcontrib><creatorcontrib>Sotiraki, S</creatorcontrib><creatorcontrib>Himonas, C</creatorcontrib><creatorcontrib>Fthenakis, G.C</creatorcontrib><collection>AGRIS</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Veterinary parasitology</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Papadopoulos, E</au><au>Sotiraki, S</au><au>Himonas, C</au><au>Fthenakis, G.C</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Treatment of small lungworm infestation in sheep by using moxidectin</atitle><jtitle>Veterinary parasitology</jtitle><addtitle>Vet Parasitol</addtitle><date>2004-05-26</date><risdate>2004</risdate><volume>121</volume><issue>3</issue><spage>329</spage><epage>336</epage><pages>329-336</pages><issn>0304-4017</issn><eissn>1873-2550</eissn><abstract>The use of moxidectin (MXD) in the treatment of small lungworm infestation (
Cystocaulus ocreatus,
Muellerius capillaris,
Neostrongylus linearis and
Protostronglylus rufescens) in sheep, was evaluated. Twenty-one sheep naturally infested with small lungworms, were divided into three groups (
n=7) and treated as follows: group A with moxidectin 1% injectable solution at a dose rate of 0.2
mg
kg
−1 bodyweight, group B with moxidectin 0.1% oral drench at a dose rate of 0.2
mg
kg
−1 bodyweight and group C being controls. Before treatment, mean faecal larval counts were 30.7, 21.1 and 26.7
lpg in group A, B and C, respectively; 14 days after treatment respective counts were 0.4, 2.3 and 63.0
lpg, (percentage reduction after moxidectin administration >96.0%); 60 days after treatment respective counts were 0.0, 0.0 and 26.4
lpg, (percentage reduction after moxidectin administration 100%). It is concluded that treatment of small lungworm infestation of sheep can be effected by using moxidectin.</abstract><cop>Netherlands</cop><pub>Elsevier B.V</pub><pmid>15135874</pmid><doi>10.1016/j.vetpar.2004.02.026</doi><tpages>8</tpages></addata></record> |
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| ispartof | Veterinary parasitology, 2004-05, Vol.121 (3), p.329-336 |
| issn | 0304-4017 1873-2550 |
| language | eng |
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| source | ScienceDirect Freedom Collection 2022-2024 |
| subjects | Administration, Oral animal parasitic nematodes Animals Antinematodal Agents - therapeutic use Control methods-Nematoda Cystocaulus Cystocaulus ocreatus drug efficacy drug formulations drug therapy fecal larval count Feces - parasitology Female Injections, Subcutaneous - veterinary Lung - parasitology Lungworms Macrolides - therapeutic use Moxidectin Muellerius capillaris nematode infections nematode larvae Neostrongylus Neostrongylus linearis oral administration Parasite Egg Count - veterinary population density Protostrongylus Protostrongylus rufescens Sheep Sheep Diseases - drug therapy Sheep Diseases - parasitology Sheep-Nematoda Statistics, Nonparametric subcutaneous injection Trachea - parasitology Trichostrongyloidea - growth & development Trichostrongyloidiasis - drug therapy Trichostrongyloidiasis - parasitology Trichostrongyloidiasis - veterinary |
| title | Treatment of small lungworm infestation in sheep by using moxidectin |
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