Regulation and function of somatostatin receptors

This review summarizes the latest advances that have been made to elucidate the somatostatinergic system in respect to somatostatin receptor evolution, the development of receptor agonists/antagonists, receptor regulation, signal transduction, effects on cell proliferation, receptor–receptor or rece...

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Bibliographic Details
Published in:Journal of neurochemistry 2004-06, Vol.89 (5), p.1057-1091
Main Authors: Olias, Gisela, Viollet, Cécile, Kusserow, Heike, Epelbaum, Jacques, Meyerhof, Wolfgang
Format: Article
Language:English
Subjects:
Animals
Biological and medical sciences
Cell Division - physiology
Cell receptors
Cell structures and functions
Central Nervous System - metabolism
evolution
Fundamental and applied biological sciences. Psychology
G protein‐coupled receptor
Gastrointestinal Tract - metabolism
Humans
Ligands
Molecular and cellular biology
neuropeptide
Neuropeptide receptors
physiological function
receptor regulation
Receptors, Somatostatin - drug effects
Receptors, Somatostatin - metabolism
Receptors, Somatostatin - physiology
Signal Transduction - physiology
somatostatin
Somatostatin - metabolism
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Summary:This review summarizes the latest advances that have been made to elucidate the somatostatinergic system in respect to somatostatin receptor evolution, the development of receptor agonists/antagonists, receptor regulation, signal transduction, effects on cell proliferation, receptor–receptor or receptor–protein interactions and receptor function.
ISSN:0022-3042
1471-4159
DOI:10.1111/j.1471-4159.2004.02402.x