Bacteriologic Findings Associated with Chronic Bacterial Maxillary Sinusitis in Adults

An open-label, multicenter study was performed to assess bacteriologic findings associated with chronic bacterial maxillary sinusitis in adults. Seventy aerobic (52.2%) and 64 anaerobic (47.8%) pathogens were recovered from clinically evaluable patients at baseline (before therapy). The most commonl...

Full description

Saved in:
Bibliographic Details
Published in:Clinical infectious diseases 2002-08, Vol.35 (4), p.428-433
Main Authors: Finegold, S. M, Flynn, M. J, Rose, F. V, Jousimies-Somer, H, Jakielaszek, C, McTeague, M, Wexler, H. M, Berkowitz, E, Wynne, B
Format: Article
Language:English
Subjects:
Adult
Aerobic bacteria
Amoxicillin-Potassium Clavulanate Combination - therapeutic use
Anaerobic bacteria
Bacteria, Aerobic - drug effects
Bacteria, Anaerobic - drug effects
Bacterial diseases
Biological and medical sciences
Chronic Disease
Drug Resistance, Bacterial
Drug Therapy, Combination - therapeutic use
Ent and stomatologic bacterial diseases
Enzyme Inhibitors - therapeutic use
Haemophilus influenzae
Human bacterial diseases
Humans
Infectious diseases
Major Articles
Maxillary sinus
Maxillary Sinusitis - microbiology
Medical sciences
Microbial Sensitivity Tests
Pathogens
Penicillin G - pharmacology
Prevotella
Sinuses
Sinusitis
Streptococcus
Symptoms
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:An open-label, multicenter study was performed to assess bacteriologic findings associated with chronic bacterial maxillary sinusitis in adults. Seventy aerobic (52.2%) and 64 anaerobic (47.8%) pathogens were recovered from clinically evaluable patients at baseline (before therapy). The most commonly isolated anaerobes were Prevotella species (31.1%), anaerobic streptococci (21.9%), and Fusobacterium species (15.6%). The aerobes most frequently recovered included Streptococcus species (21.4%), Haemophilus influenzae (15.7%), Pseudomonas aeruginosa (15.7%), and Staphylococcus aureus and Moraxella catarrhalis (10.0% each). Recurrences of signs or symptoms of bacterial maxillary sinusitis associated with anaerobes were twice as frequent as were those associated with aerobes when counts of anaerobes were ⩾103 cfu/mL. A pathogenic role for Granulicatella species in cases of chronic sinusitis was documented for the first time
ISSN:1058-4838
1537-6591
DOI:10.1086/341899