Bacteriologic Findings Associated with Chronic Bacterial Maxillary Sinusitis in Adults

• Published in: Clinical infectious diseases 2002-08, Vol.35 (4), p.428-433
• Main Authors: Finegold, S. M, Flynn, M. J, Rose, F. V, Jousimies-Somer, H, Jakielaszek, C, McTeague, M, Wexler, H. M, Berkowitz, E, Wynne, B
• Format: Article
• Language: English
• Subjects: Adult; Aerobic bacteria; Amoxicillin-Potassium Clavulanate Combination - therapeutic use; Anaerobic bacteria; Bacteria, Aerobic - drug effects; Bacteria, Anaerobic - drug effects; Bacterial diseases; Biological and medical sciences; Chronic Disease; Drug Resistance, Bacterial; Drug Therapy, Combination - therapeutic use; Ent and stomatologic bacterial diseases; Enzyme Inhibitors - therapeutic use; Haemophilus influenzae; Human bacterial diseases; Humans; Infectious diseases; Major Articles; Maxillary sinus; Maxillary Sinusitis - microbiology; Medical sciences; Microbial Sensitivity Tests; Pathogens; Penicillin G - pharmacology; Prevotella; Sinuses; Sinusitis; Streptococcus; Symptoms
• ISSN: 1058-4838; 1537-6591
• DOI: 10.1086/341899

An open-label, multicenter study was performed to assess bacteriologic findings associated with chronic bacterial maxillary sinusitis in adults. Seventy aerobic (52.2%) and 64 anaerobic (47.8%) pathogens were recovered from clinically evaluable patients at baseline (before therapy). The most commonly isolated anaerobes were Prevotella species (31.1%), anaerobic streptococci (21.9%), and Fusobacterium species (15.6%). The aerobes most frequently recovered included Streptococcus species (21.4%), Haemophilus influenzae (15.7%), Pseudomonas aeruginosa (15.7%), and Staphylococcus aureus and Moraxella catarrhalis (10.0% each). Recurrences of signs or symptoms of bacterial maxillary sinusitis associated with anaerobes were twice as frequent as were those associated with aerobes when counts of anaerobes were ⩾103 cfu/mL. A pathogenic role for Granulicatella species in cases of chronic sinusitis was documented for the first time