Treatment of acquired perforating dermatosis with narrowband ultraviolet B

Acquired perforating dermatosis is difficult to treat. We describe effective therapy of acquired perforating dermatosis with narrowband UVB in 5 patients. Phototherapy was given 2 or 3 times weekly. The dose was started at 400 mJ/cm 2 and increased to a maximum of 1500 mJ/cm 2. All lesions disappear...

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Bibliographic Details
Published in:Journal of the American Academy of Dermatology 2004-06, Vol.50 (6), p.892-894
Main Authors: Ohe, Shuichi, Danno, Kiichiro, Sasaki, Hiroko, Isei, Taiki, Okamoto, Hiroyuki, Horio, Takeshi
Format: Article
Language:English
Subjects:
Aged
Biological and medical sciences
Dermatology
Diabetes Complications
Female
Humans
Kidney Failure, Chronic - complications
Male
Medical sciences
Middle Aged
Renal Dialysis
Skin Diseases - radiotherapy
Ultraviolet Therapy - methods
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Summary:Acquired perforating dermatosis is difficult to treat. We describe effective therapy of acquired perforating dermatosis with narrowband UVB in 5 patients. Phototherapy was given 2 or 3 times weekly. The dose was started at 400 mJ/cm 2 and increased to a maximum of 1500 mJ/cm 2. All lesions disappeared completely after 10 to 15 exposures without adverse effects. Two patients with diabetes mellitus but without chronic renal failure experienced no recurrence until 5 and 10 months after stopping the phototherapy. One patient undergoing hemodialysis for chronic renal failure experienced a recurrence of pruritus and small papules after 1 month. Two patients undergoing hemodialysis showed no recurrence during narrowband UVB maintenance therapy until 7 and 8 months.
ISSN:0190-9622
1097-6787
DOI:10.1016/j.jaad.2004.02.009