Iron(III) complexing ability of carbohydrate derivatives

A solution study on the coordinative ability of galactaric acid (GalAH 2), d-glucosamine (GlcN) and d-glucosaminic acid (GlcNAH) toward Fe 3+ ion is reported. UV spectroscopic study provides useful information to identify complex species formation and their stability constants are determined by mean...

Full description

Saved in:
Bibliographic Details
Published in:Journal of inorganic biochemistry 2004-06, Vol.98 (6), p.1002-1008
Main Authors: Ferrari, E., Saladini, M.
Format: Article
Language:English
Subjects:
Carbohydrates - chemistry
d-glucosamine
d-glucosaminic acid
Fe 3+ complexes
Galactaric acid
Hydrogen-Ion Concentration
Iron - chemistry
Iron Chelating Agents - chemistry
Molecular Structure
Organometallic Compounds - chemistry
Potentiometric study
Potentiometry
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:A solution study on the coordinative ability of galactaric acid (GalAH 2), d-glucosamine (GlcN) and d-glucosaminic acid (GlcNAH) toward Fe 3+ ion is reported. UV spectroscopic study provides useful information to identify complex species formation and their stability constants are determined by means of potentiometric measurements. GalAH 2 behaves as chelating ligand through carboxylic oxygen and α-hydroxylic oxygen in the protonated or dissociated form depending on pH value. Two complex species [Fe 2GalA(OH) 4] and Na[FeGalAH −2] · 2H 2O are also isolated in the solid state and characterised through IR spectroscopy. GlcNAH also binds the Fe 3+ ion through carboxylic and hydroxylic groups, while NH 2 group is probably involved in metal coordiantion up to pH 4. GlcN demonstrates low ligating ability at acidic pH and does not prevent metal hydroxyde precipitation.
ISSN:0162-0134
1873-3344
DOI:10.1016/j.jinorgbio.2004.02.017