Reperfusion assessment using myocardial contrast echocardiography in patients with ST-segment elevation acute myocardial infarction

In this study, 29 patients underwent myocardial contrast echocardiography after presentation with ST-segment elevation acute myocardial infarction but before coronary angiography using a continuous infusion of microbubbles and real-time imaging with a low mechanical index. Patients with transmural p...

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Bibliographic Details
Published in:The American journal of cardiology 2004-06, Vol.93 (11), p.1401-1403
Main Authors: Main, Michael L, Kusnetzky, Lisa L, Dillon, Drusilla, Daniel, William C
Format: Article
Language:English
Subjects:
Biological and medical sciences
Cardiology. Vascular system
Contrast Media
Coronary Circulation
Coronary heart disease
Creatine Kinase - blood
Creatine Kinase, MB Form
Echocardiography
Electrocardiography
Feasibility Studies
Female
Fluorocarbons
Heart
Heart attacks
Humans
Indexes
Isoenzymes - blood
Male
Medical sciences
Microspheres
Middle Aged
Myocardial Infarction - diagnostic imaging
Myocardial Infarction - drug therapy
Myocardial Infarction - physiopathology
Myocardial Reperfusion
Patients
Prospective Studies
Real time
Thrombolytic Therapy
Ultrasonic imaging
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Description
Summary:In this study, 29 patients underwent myocardial contrast echocardiography after presentation with ST-segment elevation acute myocardial infarction but before coronary angiography using a continuous infusion of microbubbles and real-time imaging with a low mechanical index. Patients with transmural perfusion defects at presentation subsequently had much larger infarctions (as measured by peak creatine phosphokinase-MB fraction) than did those with normal perfusion, indicating that myocardial contrast echocardiography may be a useful means to determine adequacy of reperfusion after thrombolytic therapy and in the selection of patients for adjunctive treatment, such as “rescue angioplasty.”
ISSN:0002-9149
1879-1913
DOI:10.1016/j.amjcard.2004.02.040