Monitoring of respiratory variations of aortic blood flow velocity using esophageal Doppler

• Published in: Intensive care medicine 2004-06, Vol.30 (6), p.1182-1187
• Main Authors: SLAMA, Michel, MASSON, Henri, ANDREJAK, Michel, TEBOUL, Jean-Louis, ARNOULD, Marie-Luce, NAIT-KAOUDJT, Rachida, COLAS, Bouchra, PELTIER, Marcel, TRIBOUILLOY, Christophe, SUSIC, Dinko, FROHLICH, Edward
• Format: Article
• Language: English
• Subjects: Analysis of Variance; Anesthesia. Intensive care medicine. Transfusions. Cell therapy and gene therapy; Animals; Aorta, Thoracic - diagnostic imaging; Biological and medical sciences; Blood Flow Velocity; Echocardiography, Transesophageal; Female; Hemodynamics; Hypovolemia - diagnostic imaging; Hypovolemia - physiopathology; Intensive care medicine; Medical sciences; Monitoring, Physiologic - methods; Positive-Pressure Respiration; Rabbits; Reproducibility of Results; Stroke Volume
• ISSN: 0342-4642; 1432-1238
• DOI: 10.1007/s00134-004-2190-z

The purpose of this study was to determine whether monitoring of respiratory changes in aortic blood flow velocity, recorded by esophageal Doppler, could be used to detect changes in volume depletion. Animal study. After general anesthesia and tracheotomy, ten New Zealand female rabbits, weighing 4-4.5 kg were studied under mechanical ventilation at a fixed tidal volume; during this time 5-ml blood samples were withdrawn (in increments up to a total of 30 ml) and then retransfused. At each step, systolic (SBP), diastolic (DBP), pulse (PP) pressures and maximum descending aortic blood flow (V) were recorded. Respiratory changes of V (DeltaV), SBP (DeltaSBP) and PP (DeltaPP) were calculated as the difference of maximal and minimal values divided by their respective means and expressed as a percentage. The amount of blood withdrawn correlated negatively with SBP, DBP, PP and V and positively with DeltaSBP, DeltaPP and DeltaV. Among these parameters, DeltaV correlated best with the amount of blood withdrawn ( r=0.89, p