Significance of hypocarbia in the development of periventricular leukomalacia in preterm infants

Background : Despite rapid advances in the management of preterm infants, periventricular leukomalacia (PVL) remains a considerable problem in neonatal intensive care. The aim of this study was to determine whether hypocarbia is associated with the development of PVL in mechanically ventilated, pret...

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Bibliographic Details
Published in:Pediatrics international 2004-06, Vol.46 (3), p.268-273
Main Authors: Giannakopoulou, Christina, Korakaki, Eftichia, Manoura, Antonia, Bikouvarakis, Stellios, Papageorgiou, Maria, Gourgiotis, Dimitrios, Hatzidaki, Eleftheria
Format: Article
Language:English
Subjects:
Case-Control Studies
Female
Humans
Hypocapnia - complications
hypocarbia
Infant, Newborn
Infant, Premature
Infant, Premature, Diseases - blood
Infant, Premature, Diseases - diagnostic imaging
Infant, Premature, Diseases - etiology
Leukomalacia, Periventricular - blood
Leukomalacia, Periventricular - diagnostic imaging
Leukomalacia, Periventricular - etiology
Male
periventricular leukomalacia
prematurity
Respiration, Artificial
Risk Factors
Ultrasonography
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Summary:Background : Despite rapid advances in the management of preterm infants, periventricular leukomalacia (PVL) remains a considerable problem in neonatal intensive care. The aim of this study was to determine whether hypocarbia is associated with the development of PVL in mechanically ventilated, preterm infants and to emphasize the importance of avoiding this disturbance. Methods : The authors evaluated 52 mechanically ventilated infants with a gestational age of
ISSN:1328-8067
1442-200X
DOI:10.1111/j.1442-200x.2004.01886.x