Antimicrobial susceptibility of Haemophilus parasuis and Histophilus somni from pigs and cattle in Denmark

• Published in: Veterinary microbiology 2004-06, Vol.101 (2), p.143-146
• Main Authors: Aarestrup, Frank M, Seyfarth, Anne Mette, Angen, Øystein
• Format: Article
• Language: English
• Subjects: ampicillin; Animals; Anti-Bacterial Agents - pharmacology; Bacteriology; Biological and medical sciences; Cattle; Cattle Diseases - microbiology; ceftiofur; ciprofloxacin; Denmark; Drug Resistance, Bacterial; erythromycin; florfenicol; Fundamental and applied biological sciences. Psychology; Haemophilus Infections - microbiology; Haemophilus Infections - veterinary; Haemophilus parasuis; Haemophilus parasuis - drug effects; Haemophilus parasuis - growth & development; Haemophilus parasuis - isolation & purification; Haemophilus somnus - drug effects; Haemophilus somnus - growth & development; Haemophilus somnus - isolation & purification; Histophilus somni; Microbial Sensitivity Tests - veterinary; Microbiology; Miscellaneous; pathogens; spectinomycin; Susceptibility testing; Swine; Swine Diseases - microbiology; tetracycline; tiamulin
• ISSN: 0378-1135; 1873-2542
• DOI: 10.1016/j.vetmic.2004.02.012

A total of 52 Haemophilus parasuis and 80 Histophilus somni isolates were tested for antimicrobial susceptibility by MIC-determinations. None of the isolates were resistant to ampicillin, ceftiofur, ciprofloxacin, erythromycin, florphenicol, penicillin, spectinomycin, tetracycline, tiamulin, or tilmicosin. Two H. parasuis isolates were resistant to trimethoprim+sulfamethoxazole. Six H. parasuis isolates had reduced susceptibility (0.06–0.5 μg/ml) to ciprofloxacin and 10 reduced susceptibility to TMP+sulfamethoxazole (1–2 μg/ml). This study showed that Danish isolates of H. parasuis and H. somni in general are fully susceptible to antimicrobial agents currently used for treatment of infections with these pathogens.